Ethnopharmacological relevance Liver disease is a major cause of illness and death
worldwide which accounts for approximately 2 million deaths per year worldwide, 1 million …

Hepatoprotective effects of natural compounds have been frequently attributed to their
antioxidant properties and the ability to mobilize endogenous antioxidant defense system …

Although Doxorubicin (DOX) is a widespread drug used in the treatment of cancer, its
clinical use is restricted due to its common side effects. In addition, administrating DOX with …

Despite great progress in understanding the activation of hepatic stellate cells (HSCs)
during liver fibrosis, therapeutic approaches to inhibit HSC activation remain very limited …

Obesity is a major health issue that contributes significantly to increased mortality and
morbidity worldwide. Obesity is caused by uncontrolled adipogenesis and lipogenesis …

Polyphenols, chemically characterized by a polyhydroxylated phenolic structure, are well
known for their widespread pharmacological properties: anti-inflammatory, antibiotic …

The Global cancer incidence and mortality data released by the World Health Organization
proposes that out of 18.1 million new cancer cases diagnosed, 9.8 million deaths occurred …

AIM To investigate whether morin can reduce hepatic fibrosis by activating the NF-E2-
related factor 2 (Nrf2) signaling pathway. METHODS Twenty male Sprague-Dawley rats …

T helper (Th) 17 cells highly contribute to the immunopathology of rheumatoid arthritis.
Morin, a natural flavonoid, owns well anti-arthritic action but unclear effect on Th17 …

Silymarin (Sy) shows limited water solubility and poor oral bioavailability. Water-soluble
hydroxypropyl (HPBCD) and randomly methylated (RAMEB) β-cyclodextrins were designed …