Acylcarnitines play an essential role in regulating the balance of intracellular sugar and lipid
metabolism. They serve as carriers to transport activated long-chain fatty acids into …

The most effective way to combat β-thalassemias is to prevent the birth of children with
thalassemia major. Therefore, a cost-effective screening method is essential to identify β …

Introduction Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal disease of
hematopoietic cells with a variable clinical spectrum characterized by intravascular …

Thalassemia is one of the most prevalent genetic disorders in Iran. The birth of a child with
thalassemia major is associated with many problems for the family, and society. In the …

Acylcarnitines are closely related to many metabolic diseases and likely to be good
biomarkers for clinical diagnosis. Studies on acylcarnitines may help deepen the …

Introduction α-Thalassemia is the most common inherited disease in southern China. The
severest form is hemoglobin (Hb) Bart's disease, in which the affected fetuses almost always …

Hemoglobinopathies include all genetic diseases of hemoglobin and are grouped into
thalassemia syndromes and structural hemoglobin variants. The β-thalassemias constitute a …

Different mutations in the beta-globin gene impose clinical heterogeneity in the affected
individuals, such as patients with Hb E disease are asymptomatic and non-transfusion …

Аннотация Исследование особенностей карнитинового обмена у представителей
отдельных видов спорта позволяет изучать воздействие различных по характеру …

Beta thalassemia is an inherited blood disorder that affects synthesis of the beta chain in the
production of haemogoblin, leading to the production of deficient RBCs (red blood cells) that …