Tablets are the most widely utilized solid oral dosage forms because of the advantages of
self-administration, stability, ease of handling, transportation, and good patient compliance …

Abstract Background Quality by Design (QbD) is a pharmaceutical quality management
system that predicts, controls, and systematically responds to risks that may occur in the …

This work aimed to develop dual drug-loaded nanostructured lipid carriers of raloxifene and
naringin (RLX/NRG NLCs) for breast cancer. RLX/NRG NLCs were prepared using …

Abstract Box–Behnken designs (BBDs) are the very efficient response surface design which
provides information exclusively on the effect of experiment variables and overall …

Superficial fungal diseases of the skin and nails are an increasingly common occurrence
globally, requiring effective topical treatment to avoid systemic adverse effects. Polymeric …

In the present work, an attempt was undertaken to improve the oral bioavailability and
anticancer activity of abiraterone acetate. Solid lipid nanoparticles (SLNs) were developed …

The present study focuses on optimizing, developing, and validating a sensitive and specific
reversed-phase high-performance liquid chromatography (RP-HPLC) method for the …

The development and adoption of digital twins (DT) for Quality-by-Design (QbD)-based
processes with flexible operating points within a proven acceptable range (PAR) and …

Engineered nano-sized liposomes have attained the highest success rate in
commercialization among the reported nanomedicines. However, developing industrially …

This paper presents a machine learning-based image analysis method to monitor the
particle size distribution of fluidized granules. The key components of the direct imaging …