Liver fluke infection caused by Opisthorchis viverrini is a major public health problem in
Thailand and adjacent countries. In addition to infection-associated morbidity, infection with …

Aminopeptidases are enzymes that selectively hydrolyze an amino acid residue from the N-
terminus of proteins and peptides. They are important for the proper functioning of …

Exosomes are small vesicles of endocytic origin, which are released into the extracellular
environment and mediate a variety of physiological and pathological conditions. Here we …

Schistosomes infect hundreds of millions of people in the developing world. Transmission of
these parasites relies on a stem cell-driven, clonal expansion of larvae inside a molluscan …

Schistosomiasis (bilharzia) is a tropical disease caused by trematode parasites
(Schistosoma) that affects hundreds of millions of people in the developing world. Currently …

The two parasitic trematodes, Clonorchis sinensis and Opisthorchis viverrini, have a major
impact on the health of tens of millions of humans throughout Asia. The greatest impact is …

The ability of the mammalian blood fluke Schistosoma japonicum to survive in the
inhospitable environment of the mammalian bloodstream can be attributed, at least in part …

Background The possible emergence of resistance to the only available drug for
schistosomiasis spurs drug discovery that has been recently incentivized by the availability …

Liver flukes of animals are parasitic flatworms (Platyhelminthes: Digenea) of major
socioeconomic importance in many countries. Key representatives, such as Fasciola …

More than two billion people (one-third of humanity) are infected with parasitic roundworms
or flatworms, collectively known as helminth parasites. These infections cause diseases that …