Mechanisms of drug release in nanotherapeutic delivery systems

PT Wong, SK Choi - Chemical reviews, 2015 - ACS Publications
Targeted drug delivery refers to an established therapeutic strategy that develops platforms
and nanoscale devices for selective delivery of small drug molecules and therapeutic genes …

Mesoporous silica nanoparticles in medicine—Recent advances

V Mamaeva, C Sahlgren, M Lindén - Advanced drug delivery reviews, 2013 - Elsevier
MSNs have attracted increasing interest as drug carriers due to promising in vivo results in
small-animal disease models, especially related to cancer therapy. In most cases small …

Cytokines as biomarkers of nanoparticle immunotoxicity

M Elsabahy, KL Wooley - Chemical Society Reviews, 2013 - pubs.rsc.org
Nanoscale objects, whether of biologic origin or synthetically created, are being developed
into devices for a variety of bionanotechnology diagnostic and pharmaceutical applications …

Delivery of therapeutic agents by nanoparticles made of grapefruit-derived lipids

Q Wang, X Zhuang, J Mu, ZB Deng, H Jiang… - Nature …, 2013 - nature.com
Although the use of nanotechnology for the delivery of a wide range of medical treatments
has potential to reduce adverse effects associated with drug therapy, tissue-specific delivery …

Emerging strategies in developing multifunctional nanomaterials for cancer nanotheranostics

MJY Ang, SY Chan, YY Goh, Z Luo, JW Lau… - Advanced Drug Delivery …, 2021 - Elsevier
Cancer involves a collection of diseases with a common trait–dysregulation in cell
proliferation. At present, traditional therapeutic strategies against cancer have limitations in …

Bio-conjugated quantum dots for cancer research: detection and imaging

Z Liang, MB Khawar, J Liang, H Sun - Frontiers in Oncology, 2021 - frontiersin.org
Ultrasound, computed tomography, magnetic resonance, and gamma scintigraphy-based
detection and bio-imaging technologies have achieved outstanding breakthroughs in recent …

Recent insights on indirect mechanisms in developmental toxicity of nanomaterials

BB Dugershaw, L Aengenheister, SSK Hansen… - Particle and Fibre …, 2020 - Springer
Background Epidemiological and animal studies provide compelling indications that
environmental and engineered nanomaterials (NMs) pose a risk for pregnancy, fetal …

A comparative study of five physiological key parameters between four different human trophoblast-derived cell lines

M Rothbauer, N Patel, H Gondola, M Siwetz… - Scientific reports, 2017 - nature.com
The human placenta plays a crucial role as the interface between mother and fetus. It
represents a unique tissue that undergoes morphological as well as functional changes on …

[HTML][HTML] A perspective on the developmental toxicity of inhaled nanoparticles

KS Hougaard, L Campagnolo, P Chavatte-Palmer… - Reproductive …, 2015 - Elsevier
This paper aimed to clarify whether maternal inhalation of engineered nanoparticles (NP)
may constitute a hazard to pregnancy and fetal development, primarily based on …

Nanoparticles in pregnancy: the next frontier in reproductive therapeutics

N Pritchard, T Kaitu'u-Lino, L Harris… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Nanotechnology involves the engineering of structures on a molecular
level. Nanomedicine and nano-delivery systems have been designed to deliver therapeutic …