Role of monocytes and macrophages in regulating immune response following lung transplantation

S Chiu, A Bharat - Current opinion in organ transplantation, 2016 - journals.lww.com
Monocytes and macrophages are emerging as key players in mediating both the pathogen
response and sterile lung inflammation, including that arising from barotrauma and ischemia …

Mitochondrial transplantation enhances murine lung viability and recovery after ischemia-reperfusion injury

K Moskowitzova, A Orfany, K Liu… - … of Physiology-Lung …, 2020 - journals.physiology.org
The most common cause of acute lung injury is ischemia-reperfusion injury (IRI), during
which mitochondrial damage occurs. We have previously demonstrated that mitochondrial …

Precision cut lung slices: an innovative tool for lung transplant research

DJM Kollareth, AK Sharma - Frontiers in Immunology, 2024 - frontiersin.org
Lung ischemia-reperfusion injury (IRI), a common complication after lung transplantation
(LTx), plays a crucial role in both primary graft dysfunction (PGD) and chronic lung allograft …

Coordination‐Driven Nanomedicine Mitigates One‐Lung Ventilation‐Induced Lung Injury via Radicals Scavenging and Cell Pyroptosis Inhibition

Y Fan, Y Ou, T Xiao, Z Wei, LL Zhu, C Zhu, Y Ma, S Qu… - Small, 2024 - Wiley Online Library
One‐lung ventilation (OLV) during thoracic surgery often leads to post‐operative
complications, yet effective pharmacological interventions are lacking. This study reports a …

Diminazen aceturate protects pulmonary ischemia-reperfusion injury via inhibition of ADAM17-mediated angiotensin-converting enzyme 2 shedding

LF Wang, YY Sun, Q Pan, YQ Yin, XM Tian… - Frontiers in …, 2021 - frontiersin.org
Lung ischemia-reperfusion (IR) injury is induced by pulmonary artery occlusion and
reperfusion. Lung IR injury commonly happens after weaning from extracorporeal …

Creatine supplementation attenuates pulmonary and systemic effects of lung ischemia and reperfusion injury

FM Almeida, MC Oliveira-Junior, RA Souza… - The Journal of Heart and …, 2016 - Elsevier
Background Creatine (Cr) is a dietary supplement that presents beneficial effects in
experimental models of heart and brain ischemia and reperfusion (I/R) injury. It can improve …

Cardiopulmonary bypass increases endothelial dysfunction after pulmonary ischaemia-reperfusion in an animal model

J Selim, M Hamzaoui, I Boukhalfa… - European Journal of …, 2021 - academic.oup.com
OBJECTIVES Endothelial dysfunction during ischaemia-reperfusion (IR) is a major cause of
primary graft dysfunction during lung transplantation. The routine use of cardiopulmonary …

[HTML][HTML] A modified orthotopic left lung transplantation model in rats

J Li, Y Yu, L Dong, Z Lou, Q Fang, F Liang, Y Li, M Wu - Heliyon, 2024 - cell.com
To enhance the operability of the rat orthotopic left lung transplantation model, we
implemented several improvements and meticulously detailed the procedure. One hundred …

Evaluation of the value of Synechococcus 7942 as a sensitizer for photo-sonodynamic therapy against breast cancer

R Zhao, P Zhao, Z Zhou, D Liu, Y Zhou, M Zheng… - BioScience …, 2024 - jstage.jst.go.jp
This study was conducted to investigate the value of Synechococcus 7942 (Syne) as a
sensitizer for photo-sonodynamic therapy (PSDT). Syne was characterized. The efficacy of …

A mouse model of orotracheal intubation and ventilated lung ischemia reperfusion surgery

WI Liao, D Maruyama, F Kianian, C Tat… - Journal of …, 2022 - pmc.ncbi.nlm.nih.gov
Ischemia reperfusion (IR) injury frequently results from processes that involve a transient
period of interrupted blood flow. In the lung, isolated IR permits the experimental study of this …