Dissecting diagnostic heterogeneity in depression by integrating neuroimaging and genetics

AM Buch, C Liston - Neuropsychopharmacology, 2021 - nature.com
Depression is a heterogeneous and etiologically complex psychiatric syndrome, not a
unitary disease entity, encompassing a broad spectrum of psychopathology arising from …

Meta-analyses of the n-back working memory task: fMRI evidence of age-related changes in prefrontal cortex involvement across the adult lifespan

ZA Yaple, WD Stevens, M Arsalidou - NeuroImage, 2019 - Elsevier
Working memory, a fundamental cognitive function that is highly dependent on the integrity
of the prefrontal cortex, is known to show age-related decline across the typical healthy adult …

Neurobiology of the major psychoses: a translational perspective on brain structure and function—the FOR2107 consortium

T Kircher, M Wöhr, I Nenadic, R Schwarting… - European archives of …, 2019 - Springer
Genetic (G) and environmental (E) factors are involved in the etiology and course of the
major psychoses (MP), ie major depressive disorder (MDD), bipolar disorder (BD) …

Genome-wide interaction study with major depression identifies novel variants associated with cognitive function

A Thalamuthu, NT Mills, K Berger, H Minnerup… - Molecular …, 2022 - nature.com
Abstract Major Depressive Disorder (MDD) often is associated with significant cognitive
dysfunction. We conducted a meta-analysis of genome-wide interaction of MDD and …

Air pollution interacts with genetic risk to influence cortical networks implicated in depression

Z Li, H Yan, X Zhang, S Shah, G Yang… - Proceedings of the …, 2021 - National Acad Sciences
Air pollution is a reversible cause of significant global mortality and morbidity.
Epidemiological evidence suggests associations between air pollution exposure and …

Abnormal large-scale resting-state functional networks in drug-free major depressive disorder

L Luo, H Wu, J Xu, F Chen, F Wu, C Wang… - Brain imaging and …, 2021 - Springer
Major depressive disorder (MDD) is associated with aberrant function and interaction
encompassing large parts of cortical, subcortical and limbic regions that always organized …

Neural activation signatures in individuals with subclinical depression: A task-fMRI meta-analysis

C Lyu, X Lyu, Q Gong, B Gao, Y Wang - Journal of Affective Disorders, 2024 - Elsevier
Background Previous task-related functional magnetic resonance imaging (task-fMRI)
investigations have documented abnormal brain activation associated with subclinical …

Improved and residual functional abnormalities in major depressive disorder after electroconvulsive therapy

J Wang, Y Ji, X Li, Z He, Q Wei, T Bai, Y Tian… - Progress in Neuro …, 2020 - Elsevier
Electroconvulsive therapy (ECT) can induce fast remission of depression but still retain the
residual functional impairments in major depressive disorder (MDD) patients. To delineate …

Neural correlates of working memory in first episode and recurrent depression: an fMRI study

D Yüksel, B Dietsche, C Konrad, U Dannlowski… - Progress in Neuro …, 2018 - Elsevier
Background Patients suffering from major depressive disorder (MDD) show deficits in
working memory (WM) performance accompanied by bilateral fronto-parietal BOLD signal …

Gene expression has distinct associations with brain structure and function in major depressive disorder

S Liu, A Abdellaoui, KJH Verweij… - Advanced …, 2023 - Wiley Online Library
Major depressive disorder (MDD) is associated with structural and functional brain
abnormalities. MDD as well as brain anatomy and function are influenced by genetic factors …