The hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels belong to the
superfamily of voltage‐gated potassium ion channels. They are, however, activated by …

Epilepsy is considered a circuit-level dysfunction associated with imbalanced excitation-
inhibition, it is therapeutically necessary to identify key brain regions and related circuits in …

Developing neuronal networks evolve continuously, requiring that neurons modulate both
their intrinsic properties and their responses to incoming synaptic signals. Emerging …

Relating the function of neuronal cell types to information processing and behavior is a
central goal of neuroscience. In the hippocampus, pyramidal cells in CA1 and the subiculum …

Spike-timing dependent plasticity (STDP) offers a powerful means of forming and modifying
neural circuits. Experimental and theoretical studies have demonstrated its potential …

Summary α-and β-neurexins are presynaptic cell-adhesion molecules implicated in autism
and schizophrenia. We find that, although β-neurexins are expressed at much lower levels …

The excitability of the apical tuft of layer 5 pyramidal neurons is thought to play a crucial role
in behavioral performance and synaptic plasticity. We show that the excitability of the apical …

Epiretinal prostheses aim at electrically stimulating the inner most surviving retinal cells—
retinal ganglion cells (RGCs)—to restore partial sight to the blind. Recent tests in patients …

Complex spike bursts (CSBs) represent a characteristic firing pattern of hippocampal
pyramidal cells (PCs). In CA1PCs, CSBs are driven by regenerative dendritic plateau …

Retinal prostheses aim at restoring partial sight to patients that are blind due to retinal
degenerative diseases by electrically stimulating the surviving healthy retinal neurons …