Enhanced clinical assessment of hematologic malignancies through routine paired tumor and normal sequencing
Genomic profiling of hematologic malignancies has augmented our understanding of
variants that contribute to disease pathogenesis and supported development of prognostic …
variants that contribute to disease pathogenesis and supported development of prognostic …
Clinicopathologic characterisation of myeloid neoplasms with concurrent spliceosome mutations and myeloproliferative-neoplasm-associated mutations
YC Liu, GM Illar, NG Bailey - Journal of Clinical Pathology, 2020 - jcp.bmj.com
Aims Spliceosome genes (SF3B1, SRSF2, U2AF1 and ZRSR2) are commonly mutated in
myeloid neoplasms, particularly in myelodysplastic syndromes (MDS). JAK2, MPL and …
myeloid neoplasms, particularly in myelodysplastic syndromes (MDS). JAK2, MPL and …
Genomic characterization and prognostication applied to a Brazilian cohort of patients with myelofibrosis
A Nonino, PV Campregher… - International journal of …, 2020 - Springer
Genomic characterization of patients with myeloproliferative neoplasms (MPN) may lead to
better diagnostic classification, prognostic assessment, and treatment decisions. These …
better diagnostic classification, prognostic assessment, and treatment decisions. These …
[HTML][HTML] Janus kinase V617F mutation detection in patients with myelofibrosis
D Nikolova, A Yordanov, V Damyanova… - Balkan Journal of …, 2019 - ncbi.nlm.nih.gov
Myelofibrosis (MF) is characterized by a presence of an extra fibrous tissue in the bone
marrow and additional hematopoiesis. The somatic mutation in the Janus kinase 2 (JAK2) …
marrow and additional hematopoiesis. The somatic mutation in the Janus kinase 2 (JAK2) …
Análise do Comprimento Relativo de Telômeros e Investigação de Alterações Cromossômicas em Pacientes com Mielofibrose
FPLG Amorim - 2024 - icts.unb.br
A mielofibrose (MF) é uma neoplasia mieloproliferativa crônica, rara, caracterizada por
fibrose progressiva da medula óssea, hematopoiese ineficiente e sobrevida reduzida …
fibrose progressiva da medula óssea, hematopoiese ineficiente e sobrevida reduzida …
Integrating detection of copy neutral chromosomal losses in a clinical setting in leukemia and lymphoma by means of allelic imbalance and read depth ratio …
MC Hansen, O Cédile, M Ludvigsen, E Kjeldsen… - BioRxiv, 2019 - biorxiv.org
Chromosomal aberrations are common features of hematological malignancies, with several
recurrent aberrations recognized as important diagnostic or prognostic molecular markers …
recurrent aberrations recognized as important diagnostic or prognostic molecular markers …
[图书][B] Genetic aberrations in chronic myeloid neoplasms
SR Laird - 2021 - search.proquest.com
Chronic myeloid neoplasms (CMNs) are a heterogeneous group of clonal blood disorders
with diverse clinical outcomes. Genetic analysis plays a key role in the diagnosis of CMN, as …
with diverse clinical outcomes. Genetic analysis plays a key role in the diagnosis of CMN, as …
Perfil clínico e genômico de pacientes com Mielofibrose
A Nonino - 2019 - bdtd.ucb.br
RESUMO NONINO, Alexandre. Perfil Clínico e Genômico de Pacientes Com Mielofibrose.
2019. 111 folhas. Tese de Doutorado (Pós-graduação em Ciências Genômicas e …
2019. 111 folhas. Tese de Doutorado (Pós-graduação em Ciências Genômicas e …