[HTML][HTML] The communication mechanism of the gut-brain axis and its effect on central nervous system diseases: A systematic review

S Lu, Q Zhao, Y Guan, Z Sun, W Li, S Guo… - Biomedicine & …, 2024 - Elsevier
Gut microbiota is involved in intricate and active metabolic processes the host's brain
function, especially its role in immune responses, secondary metabolism, and symbiotic …

Cardiovascular Disease and Alzheimer's Disease: The Heart–Brain Axis

A Saeed, O Lopez, A Cohen… - Journal of the American …, 2023 - Am Heart Assoc
Cardiovascular disease (CVD) remains one of the leading causes of morbidity and mortality
in aging adults across the United States. Prior studies indicate that the presence of …

A meta-analysis study of the robustness and universality of gut microbiome-metabolome associations

E Muller, YM Algavi, E Borenstein - Microbiome, 2021 - Springer
Background Microbiome-metabolome studies of the human gut have been gaining
popularity in recent years, mostly due to accumulating evidence of the interplay between gut …

An epidemiological introduction to human metabolomic investigations

AD Joshi, A Rahnavard, P Kachroo, KM Mendez… - Trends in Endocrinology …, 2023 - cell.com
Metabolomics holds great promise for uncovering insights around biological processes
impacting disease in human epidemiological studies. Metabolites can be measured across …

Current status of metabolomic biomarker discovery: impact of study design and demographic characteristics

V Tolstikov, AJ Moser, R Sarangarajan, NR Narain… - Metabolites, 2020 - mdpi.com
Widespread application of omic technologies is evolving our understanding of population
health and holds promise in providing precise guidance for selection of therapeutic …

Identification of biomarkers to diagnose diseases and find adverse drug reactions by metabolomics

D Saigusa, N Matsukawa, E Hishinuma… - Drug metabolism and …, 2021 - Elsevier
Metabolomics has been widely used for investigating the biological functions of disease
expression and has the potential to discover biomarkers in circulating biofluids or tissue …

The Alzheimer's disease exposome

CE Finch, AM Kulminski - Alzheimer's & Dementia, 2019 - Elsevier
Introduction Environmental factors are poorly understood in the etiology of Alzheimer's
disease (AD) and related dementias. The importance of environmental factors in gene …

Association of metabolic dysfunction with cognitive decline and Alzheimer's disease: a review of metabolomic evidence

M Amidfar, G Askari, YK Kim - Progress in Neuro-Psychopharmacology and …, 2024 - Elsevier
The discovery of new biomarkers that can distinguish Alzheimer's disease (AD) from mild
cognitive impairment (MCI) in the early stages will help to provide new diagnostic and …

Current blockades of proteins inside nanopores for real-time metabolome analysis

S Zernia, NJ van der Heide, NS Galenkamp… - ACS …, 2020 - ACS Publications
Biological nanopores are emerging as powerful and low-cost sensors for real-time analysis
of biological samples. Proteins can be incorporated inside the nanopore, and ligand binding …

Structured long-chain omega-3 fatty acids for improvement of cognitive function during aging

I Mora, L Arola, A Caimari, X Escoté… - International journal of …, 2022 - mdpi.com
Although the human lifespan has increased in the past century owing to advances in
medicine and lifestyle, the human healthspan has not kept up the same pace, especially in …