The amyloid beta peptide: a chemist's perspective. Role in Alzheimer's and fibrillization

IW Hamley - Chemical reviews, 2012 - ACS Publications
This review is concerned with the role of fibrillization of the amyloid β (Aβ)-peptide in
Alzheimer's disease (AD). The perspective is that of a physical chemist, and one aim is to …

Retinal changes in Alzheimer's disease—integrated prospects of imaging, functional and molecular advances

VB Gupta, N Chitranshi, J den Haan, M Mirzaei… - Progress in retinal and …, 2021 - Elsevier
Alzheimer's Disease (AD) is a devastating neurodegenerative disorder of the brain, clinically
characterised by cognitive deficits that gradually worsen over time. There is, at present, no …

Water quality assessment, multivariate analysis and human health risks of heavy metals in eight major lakes in Kenya

KB Githaiga, SM Njuguna, RW Gituru, X Yan - Journal of Environmental …, 2021 - Elsevier
This study evaluates water quality, concentrations and health risks of heavy metals (HMs) in
eight major lakes in Kenya namely Naivasha, Elementaita, Nakuru, Baringo, Bogoria …

Human health risk assessment for aluminium, aluminium oxide, and aluminium hydroxide

D Krewski, RA Yokel, E Nieboer… - Journal of Toxicology …, 2007 - Taylor & Francis
Full article: Human Health Risk Assessment for Aluminium, Aluminium Oxide, and Aluminium
Hydroxide Skip to Main Content Taylor and Francis Online homepage Taylor and Francis …

Aluminum and Alzheimer's disease: after a century of controversy, is there a plausible link?

L Tomljenovic - Journal of Alzheimer's Disease, 2011 - content.iospress.com
The brain is a highly compartmentalized organ exceptionally susceptible to accumulation of
metabolic errors. Alzheimer's disease (AD) is the most prevalent neurodegenerative disease …

Involvement of oxidative stress in Alzheimer disease

A Nunomura, RJ Castellani, X Zhu… - … of neuropathology & …, 2006 - academic.oup.com
Genetic and lifestyle-related risk factors for Alzheimer disease (AD) are associated with an
increase in oxidative stress, suggesting that oxidative stress is involved at an early stage of …

Neurotoxic effects of aluminium exposure as a potential risk factor for Alzheimer's disease

M Dey, RK Singh - Pharmacological Reports, 2022 - Springer
Aluminium is one of the most widely distributed elements of the Earth's crust. Its routine use
has resulted in excessive human exposure and due to the potential neurotoxic effects has …

TrkB receptor signalling: implications in neurodegenerative, psychiatric and proliferative disorders

VK Gupta, Y You, VB Gupta, A Klistorner… - International journal of …, 2013 - mdpi.com
The Trk family of receptors play a wide variety of roles in physiological and disease
processes in both neuronal and non-neuronal tissues. Amongst these the TrkB receptor in …

Alzheimer's disease, metal ions and metal homeostatic therapy

P Zatta, D Drago, S Bolognin, SL Sensi - Trends in Pharmacological …, 2009 - cell.com
Mounting evidences support the idea that endogenous 'biometals', such as copper, iron, zinc
and exogenous ones such as aluminum, can be involved as factors or cofactors in the …

Is aluminum exposure a risk factor for neurological disorders?

E Inan-Eroglu, A Ayaz - Journal of Research in Medical Sciences, 2018 - journals.lww.com
Aluminum (Al) is widely found in the nature. Although the relation between Al and
neurodegenerative diseases is still controversial, Al is related with many brain diseases …