Skin aging is one of the most evident signs of human aging. Modification of the skin during
the life span is characterized by fine lines and wrinkling, loss of elasticity and volume, laxity …

Premature graying of hair (PGH) is defined as graying of hair before the age of 20 years in
Caucasians and before 30 years in African American population. It can severely affect the …

Premature graying is an important cause of low self-esteem, often interfering with socio-
cultural adjustment. The onset and progression of graying or canities correlate very closely …

Hair follicles experience several changes with aging, the most noticeable of which is graying
of the hair shaft due to loss of melanin. Additional changes in the diameter and length of the …

Background Greying of the hair is an obvious sign of human aging. In addition to age, sex-
and ancestry-specific patterns of hair greying are also observed and the progression of …

Ageing has a huge impact on human health and economy, but its molecular basis–
regulation and mechanism–is still poorly understood. By today, more than three hundred …

Hair graying is an early and obvious phenotypic and physiological trait with age in humans.
Several recent advances in molecular biology and genetics have increased our …

Hair diversity, its style, colour, shape and growth pattern is one of our most defining
characteristics. The natural versus temporary style is influenced by what happens to our hair …

Intricate coordinated mechanisms that govern the synchrony of hair growth and melanin
synthesis remain largely unclear. These two events can be uncoupled in prematurely gray …

Hair graying holds psychosocial importance and serves as an excellent model for studying
human pigmentation and aging in an accessible miniorgan. Current evidence suggests that …