Erythropoietin: physiology and pharmacology update

JW Fisher - Experimental biology and medicine, 2003 - journals.sagepub.com
This minireview is an update of a 1997 review on erythropoletin (EPO) in this journal (1).
EPO is a 30,400-dalton glycoprotein that regulates red cell production. In the human, EPO is …

Epoetin alfa: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in nonrenal applications

A Markham, HM Bryson - Drugs, 1995 - Springer
Synopsis Epoetin alfa is a recombinant form of the principal hormone responsible for
erythrogenesis, erythropoietin. Already an established treatment for anaemia associated …

Landmark advances in the development of erythropoietin

JW Fisher - Experimental Biology and Medicine, 2010 - journals.sagepub.com
This is a Minireview covering landmarks or milestones in the development of erythropoietin
(EPO). Thirty-nine landmark advances have been identified, which cover the period 1863 …

A controlled trial of recombinant human erythropoietin after bone marrow transplantation

H Link, MA Boogaerts, AA Fauser, S Slavin, J Reiffers… - 1994 - ashpublications.org
Recombinant human erythropoietin (rHuEPO) stimulates erythropoietic bone marrow cells
and increases erythrocyte production. This prospective study was designed to evaluate the …

Erythropoietin: a paradigm for the development of practice guidelines

JD Rizzo, J Seidenfeld, M Piper… - ASH Education …, 2001 - ashpublications.org
Erythropoietin (EPO) is an endogenous hormone produced in the kidney that regulates red
blood cell production within the body. Since the cloning and first clinical introduction of …

RBC transfusion requirements after allogeneic marrow transplantation: impact of the before‐transplant Hb level on transfusion and early survival

A Xenocostas, A Yee, CJ Wong, DMC Sutton… - …, 2003 - Wiley Online Library
BACKGROUND: Most patients undergoing allogeneic marrow transplantation (alloBMT)
require transfusions of RBCs. A retrospective analysis was performed to evaluate the …

Erythropoietin therapy after allogeneic hematopoietic cell transplantation: a prospective, randomized trial

A Jaspers, F Baron, E Willems, L Seidel… - Blood, The Journal …, 2014 - ashpublications.org
We conducted a prospective randomized trial to assess hemoglobin (Hb) response to
recombinant human erythropoietin (rhEPO) therapy after hematopoietic cell transplantation …

[HTML][HTML] Anemia associated with impaired erythropoietin secretion after allogeneic stem cell transplantation: incidence, risk factors, and response to treatment

A Gaya, A Urbano-Ispizua, F Fernández-Avilés… - Biology of Blood and …, 2008 - Elsevier
After allogeneic stem cell transplantation (allo-SCT) some patients develop persistent
anemia in association with an inadequate erythropoietin (Epo) secretion. We determined the …

[HTML][HTML] Optimization of recombinant human erythropoietin therapy after allogeneic hematopoietic stem cell transplantation

F Baron, B Sautois, E Baudoux, G Matus, G Fillet… - Experimental …, 2002 - Elsevier
OBJECTIVE: Allogeneic hematopoietic stem cell transplantation (HSCT) is associated with
prolonged anemia caused by defective erythropoietin (Epo) production. We enrolled 34 …

Optimal transfusion practices after allogeneic hematopoietic cell transplantation: a systematic scoping review of evidence from randomized controlled trials

G Christou, A Iyengar, R Shorr, A Tinmouth… - …, 2016 - Wiley Online Library
BACKGROUND Integrating evidence from randomized controlled trials (RCTs) into patient
care is needed to optimize patient outcomes. Transfusion support during allogeneic …