Rethinking coagulation: from enzymatic cascade and cell-based reactions to a convergent model involving innate immune activation
J Yong, CH Toh - Blood, 2023 - ashpublications.org
Advancements in the conceptual thinking of hemostasis and thrombosis have been
catalyzed by major developments within health research over several decades. The …
catalyzed by major developments within health research over several decades. The …
Inhibitors of polyphosphate and neutrophil extracellular traps
S Vappala, SA Smith, JN Kizhakkedathu… - … in Thrombosis and …, 2023 - thieme-connect.com
The contact pathway of blood clotting has received intense interest in recent years as
studies have linked it to thrombosis, inflammation, and innate immunity. Because the contact …
studies have linked it to thrombosis, inflammation, and innate immunity. Because the contact …
Effect of factor XI inhibition on tumor cell-induced coagulation activation
J Mäder, CC Rolling, M Voigtländer… - Journal of Thrombosis …, 2024 - Elsevier
Background Cancer-associated thrombosis is a frequent complication in patients with
malignancies. While factor XI (FXI)/FXIa inhibition is efficacious in preventing postoperative …
malignancies. While factor XI (FXI)/FXIa inhibition is efficacious in preventing postoperative …
DNAse-mediated dissolution of neutrophil extracellular traps accelerates in vitro thrombin generation kinetics in trauma patients
J Goswami, TA MacArthur, C Mahony… - Shock, 2022 - journals.lww.com
Abstract Introduction: Neutrophil extracellular traps (NETs) trigger thrombin generation. We
aimed to characterize the effects of deoxyribonuclease (DNAse) on NET components (cell …
aimed to characterize the effects of deoxyribonuclease (DNAse) on NET components (cell …