Dark adaptation and its role in age-related macular degeneration

AK Nigalye, K Hess, SJ Pundlik, BG Jeffrey… - Journal of Clinical …, 2022 - mdpi.com
Dark adaptation (DA) refers to the slow recovery of visual sensitivity in darkness following
exposure to intense or prolonged illumination, which bleaches a significant amount of the …

Plasma metabolomic profiles associated with three-year progression of age-related macular degeneration

I Lains, K Mendez, A Nigalye, R Katz, VP Douglas… - Metabolites, 2022 - mdpi.com
Plasma metabolomic profiles have been shown to be associated with age-related macular
degeneration (AMD) and its severity stages. However, all studies performed to date have …

Evaluation of a mobile app for dark adaptation measurement in individuals with age-related macular degeneration

S Pundlik, P Shivshanker, A Nigalye, G Luo… - Scientific Reports, 2023 - nature.com
We present clinical evaluation of a mobile app for dark adaptation (DA) measurement in age-
related macular degeneration (AMD) patients and in older adults (age> 50 years) without …

Evaluation of cone-and rod-mediated parameters in dark adaptation testing as outcome measures in age-related macular degeneration

K Hess, T de Silva, P Grisso, H Wiley… - Ophthalmology …, 2022 - Elsevier
Purpose To investigate the suitability of 6 rod-or cone-mediated dark adaptation (DA)
parameters as outcome measures for clinical trials in age-related macular degeneration …