State-of-the-art computational models of circle of willis with physiological applications: a review

H Liu, D Wang, X Leng, D Zheng, F Chen… - Ieee …, 2020 - ieeexplore.ieee.org
Background: Various computational models of the circle of Willis (CoW) have been
developed to non-invasively estimate the blood flow and hemodynamic parameters in …

[HTML][HTML] Application of multiscale coupling models in the numerical study of circulation system

Z Chi, L Beile, L Deyu, F Yubo - Medicine in Novel Technology and …, 2022 - Elsevier
Cardiovascular diseases have become a serious threat to human health now. With the rapid
development of computer technology and medical imaging technology, the method of …

Blood flow contributions to cancer metastasis

F Font-Clos, S Zapperi, CAM La Porta - Iscience, 2020 - cell.com
The distribution patterns of cancer metastasis depend on a sequence of steps involving
adhesion molecules and on mechanical and geometrical effects related to blood circulation …

Multi-Dimensional Modeling of Cerebral Hemodynamics: A Systematic Review

J Korte, ES Klopp, P Berg - Bioengineering, 2024 - mdpi.com
The Circle of Willis (CoW) describes the arterial system in the human brain enabling the
neurovascular blood supply. Neurovascular diseases like intracranial aneurysms (IAs) can …

Numerical studies of hemodynamic alterations in pre‐and post‐stenting cerebral aneurysms using a multiscale modeling

H Yu, GP Huang, Z Yang… - International Journal for …, 2019 - Wiley Online Library
The aim of this work was to use a multiscale modeling to study the influence of stent
deployment, with generic stents, on flow distributions within the vascular network and the …

An In-Vitro Flow Study Using an Artificial Circle of Willis Model for Validation of an Existing One-Dimensional Numerical Model

H Yu, GP Huang, BR Ludwig, Z Yang - Annals of biomedical engineering, 2019 - Springer
Abstract A one-dimensional (1D) numerical model has been previously developed to
investigate the hemodynamics of blood flow in the entire human vascular network. In the …

Personalized 0D‐1D multiscale hemodynamic modeling and wave dynamics analysis of cerebral circulation for an elderly patient with dementia

X Zhang, J Liu, Z Cheng, B Wu, J Xie… - International Journal …, 2021 - Wiley Online Library
Senile dementia is associated with pronounced alterations in cerebral circulation. A
fundamental understanding of intracranial hemodynamics and wave dynamics is essential …

Personalised simulation of hemodynamics in cerebrovascular disease: lessons learned from a study of diagnostic accuracy

J Behland, VI Madai, OU Aydin, EM Akay… - Frontiers in …, 2023 - frontiersin.org
Intracranial atherosclerotic disease (ICAD) poses a significant risk of subsequent stroke but
current prevention strategies are limited. Mechanistic simulations of brain hemodynamics …

Cardiac and renal function interactions in heart failure with reduced ejection fraction: A mathematical modeling analysis

H Yu, S Basu, KM Hallow - PLoS computational biology, 2020 - journals.plos.org
Congestive heart failure is characterized by suppressed cardiac output and arterial filling
pressure, leading to renal retention of salt and water, contributing to further volume overload …

A multiscale computational modeling for cerebral blood flow with aneurysms and/or stenoses

H Yu, GP Huang, Z Yang… - International Journal for …, 2018 - Wiley Online Library
Abstract A 1‐dimensional (1D)‐3‐dimensional (3D) multiscale model for the human vascular
network was proposed by combining a low‐fidelity 1D modeling of blood circulation to …