Interplay among the oral microbiome, oral cavity conditions, the host immune response, diabetes mellitus, and its associated-risk factors—An overview

TC Negrini, IZ Carlos, C Duque, KS Caiaffa… - Frontiers in oral …, 2021 - frontiersin.org
This comprehensive review of the literature aimed to investigate the interplay between the
oral microbiome, oral cavity conditions, and host immune response in Diabetes mellitus …

Promising applications of human-derived saliva biomarker testing in clinical diagnostics

M Song, H Bai, P Zhang, X Zhou, B Ying - International Journal of Oral …, 2023 - nature.com
Saliva testing is a vital method for clinical applications, for its noninvasive features, richness
in substances, and the huge amount. Due to its direct anatomical connection with oral …

Changes in salivary amylase and glucose in diabetes: a scoping review

P Pérez-Ros, E Navarro-Flores, I Julián-Rochina… - Diagnostics, 2021 - mdpi.com
Background and Objective: Diabetes mellitus (DM) is a common long-term disease which
can be related with salivary amylase levels. DM has recently been associated with salivary …

Salivary gland proteins alterations in the diabetic milieu

M Fouani, CA Basset, AR Jurjus, LG Leone… - Journal of molecular …, 2021 - Springer
Salivary glands are considered the chief exocrine glands of the mouth and physiologically
contribute to the maintenance of the homeostasis of the oral cavity. They consist of the …

A spectroscopy based prototype for the noninvasive detection of diabetes from human saliva using nanohybrids acting as nanozyme

L Roy, S Mondal, N Bhattacharyya, R Ghosh… - Scientific reports, 2023 - nature.com
The recent prediction of diabetes to be a global pandemic invites a detection strategy
preferably non-invasive, and bloodless to manage the disease and the associated …

Salivary exosomes as a new therapy to ameliorate diabetes mellitus and combat xerostomia and submandibular salivary glands dysfunction in diabetic rats

ZA Salem, AHM Kamel, N AbuBakr - Journal of Molecular Histology, 2021 - Springer
Diabetes mellitus (DM) is one of the major metabolic diseases. Xerostomia and salivary
gland dysfunction are of its common oral complications. Exosomes, as a new therapeutic …

Non-invasive blood glucose monitoring technology in diabetes management

JC Moses, S Adibi, N Wickramasinghe, L Nguyen… - Mhealth, 2023 - pmc.ncbi.nlm.nih.gov
Diabetes is one of the leading non-communicable diseases globally, adversely impacting an
individual's quality of life and adding a considerable burden to the healthcare systems. The …

Disruption of tight junctions contributes to hyposalivation of salivary glands in a mouse model of type 2 diabetes

Y Huang, QY Mao, XJ Shi, X Cong, Y Zhang… - Journal of …, 2020 - Wiley Online Library
Tight junction (TJ) plays an important role in regulating paracellular fluid transport in salivary
glands; however, little is known about the involvement of TJs in diabetes salivary glands …

Enrichment of sulphate-reducers and depletion of butyrate-producers may be hyperglycaemia signatures in the diabetic oral microbiome

CP Vieira Lima, DC Grisi… - Journal of Oral …, 2022 - Taylor & Francis
Objectives This study aimed to investigate oral microbial signatures associated with
hyperglycaemia, by correlating the oral microbiome with three glycaemic markers. Potential …

Research progress and prospects of intelligent diabetes monitoring systems: a review

Y Zou, Z Chu, T Yang, J Guo, D Li - IEEE Sensors Journal, 2024 - ieeexplore.ieee.org
A comprehensive architecture for an intelligent diabetes monitoring system, covering various
components and their technologies is presented. Core aspects are systematically outlined …