β-lactam Resistance in Pseudomonas aeruginosa: Current Status, Future Prospects

KA Glen, IL Lamont - Pathogens, 2021 - mdpi.com
Pseudomonas aeruginosa is a major opportunistic pathogen, causing a wide range of acute
and chronic infections. β-lactam antibiotics including penicillins, carbapenems …

[HTML][HTML] The role and potential of computer-aided drug discovery strategies in the discovery of novel antimicrobials

SO Oselusi, P Dube, AI Odugbemi, KA Akinyede… - Computers in biology …, 2024 - Elsevier
Antimicrobial resistance (AMR) has become more of a concern in recent decades,
particularly in infections associated with global public health threats. The development of …

Photocatalytic and biological degradation processes to mineralize pharmaceutically active compounds and catalyst recovery: A review

R Ravi, AK Golder - Coordination Chemistry Reviews, 2025 - Elsevier
Over the past few decades, the escalating issue of water pollution has primarily originated
from the direct discharge of industrial and municipal waste. The perilous ramifications of …

Experimental and thermodynamic investigation of gemifloxacin solubility in supercritical CO2 for the production of nanoparticles

F Arabgol, M Amani, NS Ardestani… - The Journal of Supercritical …, 2024 - Elsevier
The effective use of the supercritical technology in the production of new pharmaceutical
formulations with greater bioavailability requires the determination of the solubility of …

Analytical methodologies for the estimation of oxazolidinone antibiotics as key members of anti-MRSA arsenal: a decade in review

EI El-Kimary, AN Allam, ES Khafagy… - Critical Reviews in …, 2024 - Taylor & Francis
Gram-positive bacterial infections are among the most serious diseases related with high
mortality rates and huge healthcare costs especially with the rise of antibiotic-resistant …

The Novel Chiral 2(5H)-Furanone Sulfones Possessing Terpene Moiety: Synthesis and Biological Activity

AM Khabibrakhmanova, RG Faizova… - Molecules, 2023 - mdpi.com
Over the past decades, 2 (5 H)-furanone derivatives have been extensively studied because
of their promising ability to prevent the biofilm formation by various pathogenic bacteria …

The ameliorative effects of topical gemifloxacin alone or in combination with clobetasol propionate on imiquimod-induced model of psoriasis in mice

HR Salman, AA Al-Zubaidy, AH Abbas… - … Archives of Pharmacology, 2024 - Springer
Psoriasis is a lifelong immune-driven skin condition characterized by excessive epidermal
overgrowth and inflammatory cell infiltration. Gemifloxacin is a fourth-generation …

Delafloxacin-Loaded Poly(d,l-lactide-co-glycolide) Nanoparticles for Topical Ocular Use: In Vitro Characterization and Antimicrobial Activity

AK Alshememry, MA Kalam, M Shahid, R Ali… - ACS …, 2024 - ACS Publications
Objective: We developed delafloxacin (Dela)-loaded PLGA nanoparticles (PNPs) for
potential ocular application via a topical route to treat eye infections caused by Gram …

Advancing pharmacy education by moving from sequenced “integration” to true curricular integration

D Sun, J Kinney, A Hintz, M Beck, AMH Chen - American Journal of …, 2023 - Elsevier
Objectives Traditional pharmacy education focuses on teaching content, which is
affectionately known as “silos”. Each topic area or discipline includes a course or an …

[HTML][HTML] Mutations and insights into the molecular mechanisms of resistance of Mycobacterium tuberculosis to first-line

NO Rossini, MVB Dias - Genetics and molecular biology, 2023 - SciELO Brasil
Genetically antimicrobial resistance in Mycobacterium tuberculosis is currently one of the
most important aspects of tuberculosis, considering that there are emerging resistant strains …