Pancreatic cancer (PC) is a leading cause of cancer related mortality on a global scale. The
disease itself is associated with a dismal prognosis, partly due to its silent nature resulting in …

Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the tumors with the
highest mortality, for which survival has hardly changed in the last 40 years. This high …

Telomerase is a reverse transcriptase capable of utilizing an integrated RNA component as
a template to add protective tandem telomeric single strand DNA repeats, TTAGGG, to the …

Early diagnosis of pancreatic ductal adenocarcinoma (PDAC) is essential for improving
prognosis; however, diagnosing PDAC at an early stage is challenging. In patients with …

The proportion of patients diagnosed with cancer has been shown to rise with the increasing
aging global population. Advanced age is a major risk factor for morbidity and mortality in …

It has been reported that endoscopic retrograde cholangiopancreatography (ERCP) is of
value in evaluating precise pancreatograms of the pancreatic duct (PD). Recently …

Background The fractional abundance of tumor-derived DNA in body fluids depends on the
metastatic sites and the degree of expansion. We aimed to assess the clinical significance of …

Telomerase is associated with cellular aging, and its presence limits cellular lifespan.
Telomerase by preventing telomere shortening can extend the number of cell divisions for …

Background Reliable methods are needed to identify patients with early-stage cancer or
high-grade precancerous lesions in the pancreas. Analysis of pancreatic juice to detect …

Simple Summary Cancer affects millions worldwide, with gastrointestinal cancers being
notably common. This review explores the potential of telomeres and telomerase as …