Newly emerged antiviral strategies for SARS-CoV-2: From deciphering viral protein structural function to the development of vaccines, antibodies, and small molecules
Coronavirus disease 2019 (COVID-19) caused by the infection of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has become the most severe health crisis, causing …
syndrome coronavirus 2 (SARS-CoV-2) has become the most severe health crisis, causing …
[HTML][HTML] Conformationally adaptive therapeutic peptides for diseases caused by intrinsically disordered proteins (IDPs). New paradigm for drug discovery: Target the …
The traditional model of protein structure determined by the amino acid sequence is today
seriously challenged by the fact that approximately half of the human proteome is made up …
seriously challenged by the fact that approximately half of the human proteome is made up …
Computational analysis of spike protein of SARS-CoV-2 (Omicron variant) for development of peptide-based therapeutics and diagnostics
In the last few years, the worldwide population has suffered from the SARS-CoV-2
pandemic. The WHO dashboard indicated that around 504,079,039 people were infected …
pandemic. The WHO dashboard indicated that around 504,079,039 people were infected …
Antiviral activity against SARS-CoV-2 of Conformationally constrained helical peptides derived from angiotensin-converting enzyme 2
Despite the availability of vaccines, COVID-19 continues to be aggressive, especially in
immunocompromised individuals. Therefore, the development of a specific therapeutic …
immunocompromised individuals. Therefore, the development of a specific therapeutic …
Design and selection of peptides to block the SARS-CoV-2 receptor binding domain by molecular docking
K Ramirez-Acosta, IA Rosales-Fuerte… - Beilstein Journal of …, 2022 - beilstein-journals.org
Abstract The novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is
currently one of the most contagious viruses in existence and the cause of the worst …
currently one of the most contagious viruses in existence and the cause of the worst …
Engineering an ACE2-Derived Fragment as a Decoy for Novel SARS-CoV-2 Virus
Entry inhibitors are an important resource in the response against emerging pathogens like
the novel SARS-CoV-2, which enters human cells via interaction between the surface spike …
the novel SARS-CoV-2, which enters human cells via interaction between the surface spike …
Biotherapeutic effect of cell-penetrating peptides against microbial agents: A review
Selective permeability of biological membranes represents a significant barrier to the
delivery of therapeutic substances into both microorganisms and mammalian cells …
delivery of therapeutic substances into both microorganisms and mammalian cells …
[HTML][HTML] Investigating the competition between ACE2 natural molecular interactors and SARS-CoV-2 candidate inhibitors
The SARS-CoV-2 pandemic still poses a threat to the global health as the virus continues
spreading in most countries. Therefore, the identification of molecules capable of inhibiting …
spreading in most countries. Therefore, the identification of molecules capable of inhibiting …
A Rationally Designed Synthetic Antiviral Peptide Binder Targeting the Receptor-Binding Domain of SARS-CoV-2
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a novel coronavirus,
is the causative agent responsible for the spread of the COVID19 pandemic across the …
is the causative agent responsible for the spread of the COVID19 pandemic across the …
Recent advances in the exploration and discovery of SARS-CoV-2 inhibitory peptides from edible animal proteins
X Kong, W Wang, Y Zhong, N Wang, K Bai, Y Wu… - Frontiers in …, 2024 - frontiersin.org
The severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), which causes the
coronavirus disease 2019 (COVID-19), is spreading worldwide. Although the COVID-19 …
coronavirus disease 2019 (COVID-19), is spreading worldwide. Although the COVID-19 …