Immune-mediated necrotizing myopathy: clinical features and pathogenesis

Y Allenbach, O Benveniste, W Stenzel… - Nature Reviews …, 2020 - nature.com
Immune-mediated necrotizing myopathy (IMNM) is a group of inflammatory myopathies that
was distinguished from polymyositis in 2004. Most IMNMs are associated with anti-signal …

Myositis‐specific autoantibodies: an important tool to support diagnosis of myositis

Z Betteridge, N McHugh - Journal of internal medicine, 2016 - Wiley Online Library
The idiopathic inflammatory myopathies are characterized by muscle weakness, skin
disease and internal organ involvement. Autoimmunity is known to have a role in myositis …

224th ENMC International Workshop:: Clinico-sero-pathological classification of immune-mediated necrotizing myopathies Zandvoort, The Netherlands, 14–16 …

Y Allenbach, AL Mammen, O Benveniste… - Neuromuscular …, 2018 - Elsevier
Among the idiopathic inflammatory myopathies (IIMs), immune-mediated necrotizing
myopathies (IMNMs) have been identified as important and separate entities during the past …

Statin-associated autoimmune myopathy

AL Mammen - New England Journal of Medicine, 2016 - Mass Medical Soc
Statin-Associated Autoimmune Myopathy | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

[HTML][HTML] Anti-HMGCR immune-mediated necrotising myopathy: Addressing the remaining issues

T Khoo, H Chinoy - Autoimmunity Reviews, 2023 - Elsevier
The discovery of autoantibodies directed against the 3-hydroxy-3-methylglutaryl-CoA
reductase (HMGCR) enzyme has defined a sub-set of immune-mediated necrotising …

[HTML][HTML] Autoimmune myopathies: updates on evaluation and treatment

ER McGrath, CT Doughty, AA Amato - Neurotherapeutics, 2018 - Elsevier
The major forms of autoimmune myopathies include dermatomyositis (DM), polymyositis
(PM), myositis associated with antisynthetase syndrome (ASS), immune-mediated …

Immune-mediated necrotizing myopathy: update on diagnosis and management

P Basharat, L Christopher-Stine - Current rheumatology reports, 2015 - Springer
The idiopathic inflammatory myopathies (IIMs) comprise a group of autoimmune disorders
that target skeletal muscle. They are characterized by typical laboratory and clinical features …

Statin-associated autoimmune myopathy: a systematic review of 100 cases

S Nazir, S Lohani, N Tachamo, D Poudel… - JCR: Journal of …, 2017 - journals.lww.com
Background Statins are a group of drugs that reduce the levels of triglycerides and
cholesterol in blood by inhibiting HMG-CoA reductase, an enzyme involved in rate limiting …

Diagnosis and management of immune-mediated myopathies

M Milone - Mayo Clinic Proceedings, 2017 - Elsevier
Immune-mediated myopathies (IMMs) are a heterogeneous group of acquired muscle
disorders characterized by muscle weakness, elevated creatine kinase levels, and …

Clinical characteristics of anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibodies in Chinese patients with idiopathic inflammatory myopathies

Y Ge, X Lu, Q Peng, X Shu, G Wang - PLoS One, 2015 - journals.plos.org
Objective The objective of this study was to detect the prevalence of anti-3-hydroxyl-3-
methylglutaryl coenzyme A reductase (anti-HMGCR) antibodies in Chinese patients with …