Pulmonary hypertension (PH) is a progressive disease that arises from multiple etiologies
and ultimately leads to right heart failure as the predominant cause of morbidity and …

Pulmonary hypertension (PH), defined by increased pressure within the pulmonary
vasculature, is a hemodynamic and pathophysiologic state present in a wide variety of …

Vascular atresia are often treated via transcatheter recanalization or surgical vascular
anastomosis due to congenital malformations or coronary occlusions. The cellular response …

Tissue damage in various diseases, hypoxic conditions, and some pathologies are
associated with production of endogenous factors such as the soluble form of the surface …

A computational framework is developed to consider the concurrent growth and remodelling
(G&R) processes occurring in the large pulmonary artery (PA) and right ventricle (RV), as …

Aortic aneurysms are inherently unpredictable. One can never be sure whether any given
aneurysm may rupture or dissect. Clinically, the criteria for surgical intervention are based …

Limited data exist on changes in the extracellular matrix (ECM) collagen biomarkers levels
during chronic thromboembolic pulmonary hypertension (CTEPH) development. This study …

Background Pulmonary arterial (PA) stiffness has an essential contribution to the right
ventricular (RV) failure pathogenesis. A comprehensive and multiparameter risk assessment …

Chronic thromboembolic pulmonary hypertension (CTEPH) is a debilitating disease that
progresses to right ventricular (RV) failure and death if left untreated. Little is known …

Background Pulmonary artery hypertension (PAH) is a complex disorder that can lead to
right heart failure. The generation of caveolin-1 deficient mice (CAV-1−/−) has provided an …