The growing prevalence of antimicrobial resistance (AMR) has brought with it a continual
increase in the numbers of deaths from multidrug-resistant (MDR) infections. Since the …

Due to the widespread and excessive use of antibiotics, bacterial resistance has become an
increasingly serious problem affecting public health. Amphiphilic peptide hydrogels have …

We designed a library of 24 cyclic peptides containing arginine (R) and tryptophan (W)
residues in a sequential manner [R n W n](n= 2–7) to study the impact of the hydrophilic …

While the rise of superbugs and new resistance mechanisms continues decreasing the
effectiveness of classical antibiotics, antimicrobial peptides (AMPs) are emerging as a new …

Objectives We recently designed a series of cationic deoxythymidine-based amphiphiles
that mimic the cationic amphipathic structure of antimicrobial peptides (AMPs). Among these …

Multidrug resistance against conventional antibiotics has dramatically increased the difficulty
of treatment and accelerated the need for novel antibacterial agents. The peptide Tat (47 …

The increasing severity of problems posed by drug-resistant pathogens has compelled
researchers to explore innovative approaches for infection prevention. Among these …

Motivation There has been a burgeoning interest in cyclic peptide therapeutics due to their
various outstanding advantages and strong potential for drug formation. However, it is …

Self-assembly peptides (SAPs) are an important class of hydrogels used in nanomedicine
for tissue repair and neural regeneration. Due to their unique properties, SAPs may be used …

Antimicrobial peptides (AMPs) are active short peptides that exist in microorganisms,
insects, amphibians, plants, and mammals. Some naturally occurring AMPs have low …