The carotid body (CB) is the main peripheral chemoreceptor for arterial respiratory gases O2
and CO2 and pH, eliciting reflex ventilatory, cardiovascular, and humoral responses to …

Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …

Carbon monoxide (CO) is increasingly recognized as a cell-signalling molecule akin to nitric
oxide (NO). CO has attracted particular attention as a potential therapeutic agent because of …

Carbon monoxide (CO) is continuously produced in mammalian cells during the
degradation of heme. It is a stable gaseous molecule that reacts selectively with transition …

This is the second set of Handbook of Porphyrin Science. Porphyrins, phthalocyanines and
their numerous analogues and derivatives are materials of tremendous importance in …

J. Neurochem.(2010) 10.1111/j. 1471‐4159.2010. 06580. x Abstract Nitric oxide (NO) and
carbon monoxide (CO) are well established as messenger molecules throughout the body …

The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the
blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in …

Moment-to-moment changes in local neuronal activity lead to dynamic changes in cerebral
blood flow. Emerging evidence implicates astrocytes as one of the key players in …

The heme iron complex is one of the most important cofactors in biological systems (Figure
1). The major functions of the heme iron complex are to serve as the O2 binding site for …

Epoxyeicosatrienoic acids (EETs) are cytochrome P450 metabolites of arachidonic acid that
are produced by the vascular endothelium in response to agonists such as bradykinin and …