This is the first of a projected series of canonic reviews covering all invertebrate muscle
literature prior to 2005 and covers muscle genes and proteins except those involved in …

This essay reviews the long tradition of experimental genetics of the Drosophila indirect
flight muscles (IFM). It discusses how genetics can operate in tandem with multidisciplinary …

Mutations in human survival motor neurons 1 (SMN1) cause spinal muscular atrophy (SMA)
and are associated with defects in assembly of small nuclear ribonucleoproteins (snRNPs) …

To understand neural circuits that control limbs, one must measure their activity during
behavior. Until now this goal has been challenging, because limb premotor and motor …

Mitochondrial networks provide coordinated energy distribution throughout muscle cells.
However, pathways specifying mitochondrial networks are incompletely understood and it is …

Deubiquitinating enzymes (DUBs) are proteases that control the post-translational
modification of proteins by ubiquitin and in turn regulate diverse cellular pathways. Despite a …

The indirect flight muscles (IFM) of Drosophila melanogaster provide a good genetic system
with which to investigate muscle function. Flight muscle contraction is regulated by both …

In striated muscle tropomyosin (Tm) extends along the length of F-actin-containing thin
filaments. Its location governs access of myosin binding sites on actin and, hence, force …

Myosin storage myopathy (MSM) is a congenital skeletal muscle disorder caused by
missense mutations in the β-cardiac/slow skeletal muscle myosin heavy chain rod. It is …

Dynamic changes in mitochondrial shape and size are vital for mitochondrial health and for
tissue development and function. Adult Drosophila indirect flight muscles contain densely …