Psychiatric genetics has made substantial progress in the last decade, providing new
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …

Monozygotic (MZ) twins are often thought to have identical genomes, but recent work has
shown that early post-zygotic events can result in a spectrum of DNA variants that are …

Previous genome-wide association studies of depression have primarily focused on
common variants, limiting our comprehensive understanding of the genetic architecture. In …

Working memory (WM), a key component of cognitive functions, is often impaired in
psychiatric disorders such as schizophrenia. Through a genome-guided drug repurposing …

Major depression (MD) and obesity are complex genetic disorders that are frequently
comorbid. However, the study of both diseases concurrently remains poorly addressed and …

The cost-effectiveness of whole exome sequencing (WES) remains controversial due to
variant call variability, necessitating sensitivity and specificity evaluation. WES was …

Human organ structure and function are important endophenotypes for clinical outcomes.
Genome-wide association studies (GWAS) have identified numerous common variants …

IMPORTANCE: Autism frequently co-occurs with other mental health conditions. In the
general population, these co-occurring mental health conditions are highly heritable and …

Postpartum psychosis is a severe psychiatric condition marked by the abrupt onset of
psychosis, mania, or psychotic depression following childbirth. Despite evidence for a strong …

Background Major depressive disorder (MDD) is a polygenic, and highly prevalent disorder
affecting 322 million people globally. It results in several psychological changes which …