IL-6 in inflammation, autoimmunity and cancer

T Hirano - International immunology, 2021 - academic.oup.com
IL-6 is involved both in immune responses and in inflammation, hematopoiesis, bone
metabolism and embryonic development. IL-6 plays roles in chronic inflammation (closely …

The use of renin–angiotensin–aldosterone system (RAAS) inhibitors is associated with a lower risk of mortality in hypertensive COVID‐19 patients: a systematic review …

Y Wang, B Chen, Y Li, L Zhang, Y Wang… - Journal of medical …, 2021 - Wiley Online Library
Renin–angiotensin–aldosterone system (RAAS) inhibitors, including angiotensin‐converting
enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are one of the most …

Guía práctica sobre el diagnóstico y tratamiento de la hipertensión arterial en España, 2022. Sociedad Española de Hipertensión-Liga Española para la Lucha contra …

M Gorostidi, T Gijón-Conde, A De la Sierra… - Hipertensión y riesgo …, 2022 - Elsevier
La hipertensión arterial es el principal factor de riesgo de enfermedad y muerte en España.
El diagnóstico y el tratamiento de la hipertensión arterial constituyen objetivos básicos de …

Efficacy of losartan in hospitalized patients with COVID-19–induced lung injury: a randomized clinical trial

MA Puskarich, NE Ingraham, LH Merck… - JAMA network …, 2022 - jamanetwork.com
Importance SARS-CoV-2 viral entry may disrupt angiotensin II (AII) homeostasis,
contributing to COVID-19 induced lung injury. AII type 1 receptor blockade mitigates lung …

Expression of the SARS-CoV-2 receptorACE2 in human heart is associated with uncontrolled diabetes, obesity, and activation of the renin angiotensin system

M Herman-Edelstein, T Guetta, A Barnea… - Cardiovascular …, 2021 - Springer
Background Diabetic and obese patients are at higher risk of severe disease and cardiac
injury in corona virus 2 (SARS-CoV-2) infections. Cellular entry of SARS-CoV-2 is mainly via …

Renin‐angiotensin aldosterone system inhibitors and COVID‐19: a systematic review and meta‐analysis revealing critical bias across a body of observational …

J Loader, FC Taylor, E Lampa… - Journal of the American …, 2022 - Am Heart Assoc
Background Renin‐angiotensin aldosterone system (RAAS) inhibitor—COVID‐19 studies,
observational in design, appear to use biased methods that can distort the interaction …

Association between cardiometabolic risk factors and COVID-19 susceptibility, severity and mortality: a review

Y Sharifi, M Payab, E Mohammadi-Vajari… - Journal of Diabetes & …, 2021 - Springer
The novel coronavirus, which began spreading from China Wuhan and gradually spreaded
to most countries, led to the announcement by the World Health Organization on March 11 …

Systemic arterial hypertension as a risk factor for the severe form of covid-19: scoping review

AC Ribeiro, SCSA Uehara - Revista de saude publica, 2022 - SciELO Brasil
ABSTRACT OBJECTIVE Identify whether systemic arterial hypertension is a risk factor for
the severe form of covid-19. METHODS This is a scoping review, searches were performed …

[HTML][HTML] Hypertension and COVID-19: Updates from the era of vaccines and variants

S Swamy, CA Koch, F Hannah-Shmouni… - Journal of clinical & …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible
for coronavirus disease 2019 (COVID-19) has been a major cause of morbidity and mortality …

Clinical characteristics associated with mortality of COVID-19 patients admitted to an intensive care unit of a tertiary hospital in South Africa

PS Nyasulu, BT Ayele, CF Koegelenberg, E Irusen… - PloS one, 2022 - journals.plos.org
Background Over 130 million people have been diagnosed with Coronavirus disease 2019
(COVID-19), and more than one million fatalities have been reported worldwide. South …