The translational potential of microRNAs as biofluid markers of urological tumours

A Fendler, C Stephan, GM Yousef… - Nature Reviews …, 2016 - nature.com
MicroRNAs (miRNAs) are secreted by cells in vesicles, bound in a ribonucleoprotein
complex or as free molecules. These miRNA secretion pathways are dysregulated in cancer …

miRNAs as novel biomarkers in the management of prostate cancer

X Filella, L Foj - Clinical Chemistry and Laboratory Medicine (CCLM), 2017 - degruyter.com
Abstract microRNAs (miRNAs) are small non-coding RNAs that control gene expression
posttranscriptionally and are part of the giant non codifying genoma. Cumulating data …

Prostate microbiota and prostate cancer: a new trend in treatment

B Che, W Zhang, S Xu, J Yin, J He, T Huang… - Frontiers in …, 2021 - frontiersin.org
Although the incidence and mortality of prostate cancer have gradually begun to decline in
the past few years, it is still one of the leading causes of death from malignant tumors in the …

The utility of urine-circulating miRNAs for detection of prostate cancer

K Stuopelyte, K Daniunaite, A Bakavicius… - British journal of …, 2016 - nature.com
Background: In this paper, the utility of urine-circulating microRNAs (miRNAs) as the
potential biomarker of prostate cancer (PCa), the second most prevalent male cancer …

[HTML][HTML] Extracellular MicroRNA in liquid biopsy: applicability in cancer diagnosis and prevention

A Izzotti, S Carozzo, A Pulliero… - American journal of …, 2016 - ncbi.nlm.nih.gov
One of the goals of contemporary cancer research is the development of new markers that
facilitate earlier and non-invasive diagnosis. MicroRNAs are non-coding RNA molecules …

Diagnostic, prognostic and predictive value of cell-free miRNAs in prostate cancer: a systematic review

E Endzeliņš, V Melne, Z Kalniņa, V Lietuvietis… - Molecular cancer, 2016 - Springer
Prostate cancer, the second most frequently diagnosed cancer in males worldwide, is
estimated to be diagnosed in 1.1 million men per year. Introduction of PSA testing …

Potential of miRNAs in urinary extracellular vesicles for management of active surveillance in prostate cancer patients

M Ramirez-Garrastacho, V Berge, A Linē… - British journal of …, 2022 - nature.com
Background Active surveillance is an alternative to radical treatment for patients with low-risk
prostate cancer, which could also benefit some patients with intermediate risk. We have …

Biomarkers that differentiate benign prostatic hyperplasia from prostate cancer: A literature review

CJ McNally, MW Ruddock, T Moore… - Cancer management …, 2020 - Taylor & Francis
Prediction of prostate cancer in primary care is typically based upon serum total prostate-
specific antigen (tPSA) and digital rectal examination results. However, these tests lack …

[HTML][HTML] Novel diagnostic and prognostic classifiers for prostate cancer identified by genome-wide microRNA profiling

H Kristensen, AR Thomsen, C Haldrup, L Dyrskjøt… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Purpose This study investigates the diagnostic and prognostic biomarker potential of
miRNAs in prostate cancer (PC). Results We identified several new deregulated miRNAs …

[HTML][HTML] Collagen type VI‑α1 and 2 repress the proliferation, migration and invasion of bladder cancer cells

XM Piao, B Hwang, P Jeong… - International …, 2021 - spandidos-publications.com
The bladder cancer (BCa) microenvironment comprises heterogeneous tumor cell
populations, the surrounding stroma and the extracellular matrix (ECM). Collagen, the …