Gases like H2, N2, CO2, and CO are increasingly recognized as critical feedstock in “green”
energy conversion and as sources of nitrogen and carbon for the agricultural and chemical …

Covering: up to 2022 The report provides a broad approach to deciphering the evolution of
coenzyme biosynthetic pathways. Here, these various pathways are analyzed with respect …

Nature uses multinuclear metal clusters to catalyse a number of important multielectron
redox reactions. Examples that employ complex Fe–S clusters in catalysis include the Fe …

[FeFe] hydrogenases carry out the redox interconversion of protons and molecular hydrogen
(2H++ 2e−⇌ H2) at a complex Fe–S active site known as the H-cluster. The H-cluster …

The H-cluster of [FeFe]-hydrogenase consists of a [4Fe–4S] H-subcluster linked by a
cysteinyl bridge to a unique organometallic [2Fe] H-subcluster assigned as the site of …

[FeFe]-hydrogenases use a unique organometallic complex, termed the H cluster, to
reversibly convert H2 into protons and low-potential electrons. It can be best described as a …

[FeFe] hydrogenases contain a 6-Fe cofactor that serves as the active site for efficient redox
interconversion between H2 and protons. The biosynthesis of the so-called H-cluster …

Conspectus Nature's prototypical hydrogen-forming catalysts─ hydrogenases─ have
attracted much attention because they catalyze hydrogen evolution at near zero …

Abstract [FeFe]-hydrogenases are gas-processing metalloenzymes that catalyze H2
oxidation and proton reduction (H2 release) in microorganisms. Their high turnover …

Here we describe maturation of the [FeFe]-hydrogenase from its [4Fe–4S]-bound precursor
state by using the synthetic complex [Fe2 (μ-SH) 2 (CN) 2 (CO) 4] 2− together with HydF and …