For many retinal diseases, including age-related macular degeneration (AMD), glaucoma,
and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the currently …

To test whether depletion of microglia in the optic nerve head has a beneficial effect on
retinal ganglion cell numbers and function, we depleted microglia by oral administration of …

Glaucoma is a disease associated with the loss of retinal ganglion cells (RGCs), and
remains one of the primary causes of blindness worldwide. Major research efforts are …

Despite the high probability of glaucoma-related blindness, its cause is not fully understood
and there is no efficient therapeutic strategy for neuroprotection. Vascular factors have been …

There is indication that nutritional supplements protect retinal cells from degeneration. In a
previous study, we demonstrated that dietary supplementation with an association of …

Pachychoroid spectrum diseases have been described as a new clinical entity within the
spectrum of macular disorders.“Pachychoroid” is defined as choroidal thickening associated …

This study compares four different animal models of chronic glaucoma against normal aging
over 6 months. Chronic glaucoma was induced in 138 Long–Evans rats and compared …

Investigation of neurodegeneration in glaucoma, a leading cause of irreversible blindness
worldwide, has been obfuscated by the lack of an efficient model that provides chronic, mild …

Background: To compare two prolonged animal models of glaucoma over 24 weeks of
follow-up. A novel pre-trabecular model of chronic glaucoma was achieved by injection of …

Retinal ganglion cells (RGCs) are the neurons in the retina which directly project to the brain
and transmit visual information along the optic nerve. Glaucoma, one of the leading causes …