Sepsis is a manifestation of the immune and inflammatory response to infection, which may
lead to multi‑organ failure. Health care advances have improved outcomes in critical illness …

Quiescence is an essential property of meristematic cells, which restrains the cell cycle while
retaining the capacity to divide. This crucial process not only facilitates life-long tissue …

Quiescence is a crucial survival attribute in which cell division is repressed in a reversible
manner. Although quiescence has long been viewed as an inactive state, recent studies …

Plasma membrane damage in vitrified oocytes is closely linked to mitochondrial dysfunction.
However, the mechanism underlying mitochondria-regulated membrane stability is not …

Background The role of mitochondrial dynamics, encompassing fission, fusion, and
mitophagy, in cancer progression has been extensively studied. However, the specific …

In organisms with complex life cycles, life stages that are most susceptible to environmental
stress may determine species persistence in the face of climate change. Early embryos of …

The sleep-breathing condition obstructive sleep apnea (OSA) is characterized by repetitive
upper airway collapse, which can exacerbate oxidative stress and free radical generation …

Human pluripotent stem cell (hPSC)-derived red blood cells (RBCs) possess great potential
for compensating shortages in transfusion medicine. For better RBC generation from hPSCs …

The initial contraction of the heart during the embryonic stage necessitates a substantial
energy supply, predominantly derived from mitochondrial function. However, during …

Embryos undergo pre-gastrulation cleavage cycles to generate a critical cell mass before
transitioning to morphogenesis. The molecular underpinnings of this transition have …