Background Fecal microbiota transplantation (FMT) is highly effective for treating recurrent
Clostridium difficile infection (CDI) in observational studies (> 90%), but cure rates in clinical …

Background Clostridium difficile is the leading cause of antibiotic-associated diarrhoea, both
in healthcare facilities and in the community. The recurrence rate of C. difficile infection (CDI) …

Abstract Scope In 2009, the European Society of Clinical Microbiology and Infectious
Diseases (ESCMID) published the first treatment guidance document for Clostridioides …

The gut microbiota composition of elderly hospitalized patients with Clostridium difficile
infection (CDI) exposed to previous antibiotic treatment is still poorly investigated. The aim of …

Objectives Intestinal carriage with extended spectrum β-lactamase Enterobacteriaceae
(ESBL-E) and carbapenemase-producing Enterobacteriaceae (CPE) can persist for months …

Severe and severe-complicated Clostridium difficile infection (CDI) is associated with high
morbidity and mortality. Colectomy is standard of care; however, post-surgical mortality rates …

In the past decade, fecal microbiota transplantation (FMT) has rapidly spread worldwide in
clinical practice as a highly effective treatment option against recurrent Clostridioides difficile …

Severe outbreaks and deaths have been linked to the emergence and global spread of
fluoroquinolone-resistant Clostridioides difficile over the past two decades. At the same time …

The methods of fecal microbiota transplantation (FMT) and the related results vary a lot
among centers worldwide. Therefore, methodologic standardization can improve the clinical …

Agents in development for the prevention or treatment of Clostridioides difficile infection can
be split into three broad categories: antibiotics, microbiome restoration, and vaccines. Given …