[HTML][HTML] Platelet production from induced pluripotent stem cells

N Sugimoto, K Eto - Journal of Thrombosis and Haemostasis, 2017 - Elsevier
Ex vivo production of human platelets has been pursued as an alternative measure to
resolve limitations in the supply and safety of current platelet transfusion products. To this …

[HTML][HTML] Human leucocyte antigen DR15, a possible predictive marker for immune checkpoint inhibitor–induced secondary adrenal insufficiency

S Yano, K Ashida, R Sakamoto, C Sakaguchi… - European Journal of …, 2020 - Elsevier
Abstract Background Immune checkpoint inhibitors (ICPis) induce various immune-related
adverse events (irAEs), despite their beneficial effects in treating various advanced cancers …

Virtual crossmatching and epitope analysis in kidney transplantation: What the physician involved in kidney transplantation should know?

K Nishikawa, S Masui, H Ishida - International Journal of …, 2023 - Wiley Online Library
Solid‐phase single antigen bead (SAB) assay for detection of anti‐human leukocyte antigen
(HLA) antibodies and high‐resolution HLA typing have enabled tremendous progress in …

HLA-DRB1*04:05 is involved in the development of Vogt–Koyanagi–Harada disease-like immune-related adverse events in patients receiving immune checkpoint …

M Takeuchi, A Meguro, J Nakamura, R Chikagawa… - Scientific Reports, 2023 - nature.com
Immune checkpoint inhibitors (ICIs) activate anti-tumor activity by inhibiting immune
checkpoint molecules that suppress inflammatory T-cell activity. However, ICIs can initiate …

Identification of an HLA class I allele closely involved in the autoantigen presentation in acquired aplastic anemia

Y Zaimoku, H Takamatsu, K Hosomichi… - Blood, The Journal …, 2017 - ashpublications.org
To identify HLA alleles closely involved in the autoantigen presentation in acquired aplastic
anemia (AA), we studied the HLA allelic loss frequencies of 312 AA patients, including 43 …

HLA associations, somatic loss of HLA expression, and clinical outcomes in immune aplastic anemia

Y Zaimoku, BA Patel, SD Adams… - Blood, The Journal …, 2021 - ashpublications.org
Immune aplastic anemia (AA) features somatic loss of HLA class I allele expression on bone
marrow cells, consistent with a mechanism of escape from T-cell–mediated destruction of …

Allele frequencies net database: improvements for storage of individual genotypes and analysis of existing data

EJM Dos Santos, A McCabe, FF Gonzalez-Galarza… - Human immunology, 2016 - Elsevier
Abstract The Allele Frequencies Net Database (AFND) is a freely accessible database which
stores population frequencies for alleles or genes of the immune system in worldwide …

Long-term memory CD8+ T cells specific for SARS-CoV-2 in individuals who received the BNT162b2 mRNA vaccine

N Kuse, Y Zhang, T Chikata, HT Nguyen, S Oka… - Nature …, 2022 - nature.com
Long-term memory T cells have not been well analyzed in individuals vaccinated with a
COVID-19 vaccine although analysis of these T cells is necessary to evaluate vaccine …

NK cell alloreactivity against KIR-ligand-mismatched HLA-haploidentical tissue derived from HLA haplotype-homozygous iPSCs

H Ichise, S Nagano, T Maeda, M Miyazaki, Y Miyazaki… - Stem Cell Reports, 2017 - cell.com
HLA haplotype-homozygous (HLA-homo) induced pluripotent stem cells (iPSCs) are being
prepared to be used for allogeneic transplantation of regenerated tissue into recipients …

Association of HLA-A* 31: 01 screening with the incidence of carbamazepine-induced cutaneous adverse reactions in a Japanese population

T Mushiroda, Y Takahashi, T Onuma… - JAMA …, 2018 - jamanetwork.com
Importance Carbamazepine, a commonly used antiepileptic drug, is one of the most
common causes of cutaneous adverse drug reactions (cADRs) worldwide. The allele HLA …