Carbohydrate chemistry constitutes today a “multifaceted” discipline strongly connected with
organic, pharmaceutical, and medicinal chemistry. 1 Carbohydrates are important …

Formation of carbon–carbon bonds by intramolecular additions (cyclizations) of carbon
radicals onto alkenes are important reactions in organic synthesis (Scheme 1). The rate of …

Radical cyclization reactions are among the most powerful and versatile methods for the
construction of mono‐and polycyclic systems. The advantages these reactions offer to the …

The formal synthesis of (±)-desmethylamino FR901483 (2) is described. Construction of the
unique azatricyclic skeleton of 2 was accomplished by a sequence which involved (i) …

Deoxygenations of alcohols, ie, processes that replace a hydroxyl group with hydrogen at a
saturated carbon, find applications in both total synthesis and the systematic modifications of …

Several glycoprocessing enzymes and glycoreceptors have been recognized as important
targets for therapeutic intervention. This concept has inspired the development of important …

The intramolecular reductive coupling of a series of simple or polyoxygenated oxime ethers
δ-or ε-functionalized with bromide, α, β-unsaturated ester, aldehyde, or ketone groups is …

A novel approach to 2, 4-disubstituted piperidines is reported, involving the radical
cyclization of 7-substituted-6-aza-8-bromooct-2-enoates. Cyclization with tributyltin hydride …

d-Xylose serves as a starting material for approaches to the synthesis of the glucosidase
inhibitors,(+)-cyclophellitol (1) and (+)-epi-cyclophellitol (2). An investigation of the …

In this work, we have shown that the tributyltin hydride-mediated cycloisomerization of allene-
tethered oxime ethers or hydrazones is a convenient method for the preparation of …