Executive summary The 2024 update of the Lancet Commission on dementia provides new
hopeful evidence about dementia prevention, intervention, and care. As people live longer …

The increasing number of people with dementia globally illustrates the urgent need to
reduce dementia's scale and impact. Lifetime social participation may affect dementia risk by …

Page 1 Optimizing brain health across the life course: WHO position paper World Health
Organization Page 2 World Health Organization Optimizing brain health across the life course …

Background: Education and occupational complexity are main sources of mental
engagement during early life and adulthood respectively, but research findings are not …

Immune system and blood–brain barrier dysfunction are implicated in the development of
Alzheimer's and other dementia-causing diseases, but their causal role remains unknown …

This study aims to evaluate the directionality of the association between loneliness and
cognitive performance in older adults, accounting for confounding factors. Data were from …

Background Visual impairment and interventions to preserve vision may impact dementia
risk. Thus, we aimed to explore the associations of cataract and cataract surgery with the risk …

Importance Socioeconomic status (SES) is associated with dementia. However, the role of
SES transitions in dementia is less explored; such evidence would be useful to understand …

Dysregulation of the immune system and dietary patterns that increase inflammation can
increase the risk for cognitive decline, but the mechanisms by which inflammatory nutritional …

Importance Higher educational attainment is associated with reduced dementia risk, but the
role of educational quality is understudied, presenting a major evidence gap, especially as it …