Laboratory diagnosis of Echinococcus spp. in human patients and infected animals

M Siles-Lucas, A Casulli, FJ Conraths, N Müller - Advances in parasitology, 2017 - Elsevier
Among the species composing the genus Echinococcus, four species are of human clinical
interest. The most prevalent species are Echinococcus granulosus and Echinococcus …

Host‐parasite relationship in cystic echinococcosis: an evolving story

A Siracusano, F Delunardo, A Teggi… - Journal of Immunology …, 2012 - Wiley Online Library
The larval stage of Echinococcus granulosus causes cystic echinococcosis, a neglected
infectious disease that constitutes a major public health problem in developing countries …

Enzymatic antioxidant systems in helminth parasites

L Chiumiento, F Bruschi - Parasitology Research, 2009 - Springer
Parasitic helminths have a coexistence with mammalian hosts whereby they survive for
several years in known hostile conditions of their hosts. Many explanations exist describing …

Peroxiredoxins in parasites

MC Gretes, LB Poole, PA Karplus - Antioxidants & redox signaling, 2012 - liebertpub.com
Significance: Parasite survival and virulence relies on effective defenses against reactive
oxygen and nitrogen species produced by the host immune system. Peroxiredoxins (Prxs) …

Immunomodulatory mechanisms during Echinococcus granulosus infection

A Siracusano, R Riganò, E Ortona, E Profumo… - Experimental …, 2008 - Elsevier
The pathologic events that ensue after humans ingest the eggs of Echinococcus granulosus
and continue while cystic echinococcosis develops, provide an excellent example …

Linked thioredoxin-glutathione systems in platyhelminths

G Salinas, ME Selkirk, C Chalar, RM Maizels… - TRENDS in …, 2004 - cell.com
The thioredoxin and glutathione systems play a central role in thiol-disulfide redox
homeostasis in many organisms by providing electrons to essential enzymes, and defence …

Molecular cross-talk in host–parasite relationships: the intriguing immunomodulatory role of Echinococcus antigen B in cystic echinococcosis

A Siracusano, P Margutti, F Delunardo… - International journal for …, 2008 - Elsevier
Cystic echinococcosis (CE), a zoonosis caused by the development of Echinococcus
granulosus tapeworm larvae in the internal organs of ungulates and humans, continues to …

Functional expression and characterization of Echinococcus granulosus thioredoxin peroxidase suggests a role in protection against oxidative damage

J Li, WB Zhang, A Loukas, RY Lin, A Ito, LH Zhang… - Gene, 2004 - Elsevier
A full-length cDNA sequence coding for Echinococcus granulosus thioredoxin peroxidase
(EgTPx) was isolated from a sheep strain protoscolex cDNA library by immunoscreening …

The thioredoxin system of Plasmodium falciparum and other parasites

S Rahlfs, RH Schirmer, K Becker - Cellular and Molecular Life Sciences …, 2002 - Springer
Antioxidant defence plays a crucial role in rapidly growing and multiplying organisms,
including parasites and tumor cells. Apart from reactive oxygen species (ROS) produced in …

Alternative mRNAs arising from trans-splicing code for mitochondrial and cytosolic variants of Echinococcus granulosus thioredoxin glutathione reductase

A Agorio, C Chalar, S Cardozo, G Salinas - Journal of Biological Chemistry, 2003 - ASBMB
Thioredoxin and glutathione systems are the major thiol-dependent redox systems in animal
cells. They transfer via the reversible oxidoreduction of thiols the reducing equivalents of …