A Siracusano, F Delunardo, A Teggi… - Journal of Immunology …, 2012 - Wiley Online Library
The larval stage of Echinococcus granulosus causes cystic echinococcosis, a neglected infectious disease that constitutes a major public health problem in developing countries …
L Chiumiento, F Bruschi - Parasitology Research, 2009 - Springer
Parasitic helminths have a coexistence with mammalian hosts whereby they survive for several years in known hostile conditions of their hosts. Many explanations exist describing …
MC Gretes, LB Poole, PA Karplus - Antioxidants & redox signaling, 2012 - liebertpub.com
Significance: Parasite survival and virulence relies on effective defenses against reactive oxygen and nitrogen species produced by the host immune system. Peroxiredoxins (Prxs) …
A Siracusano, R Riganò, E Ortona, E Profumo… - Experimental …, 2008 - Elsevier
The pathologic events that ensue after humans ingest the eggs of Echinococcus granulosus and continue while cystic echinococcosis develops, provide an excellent example …
The thioredoxin and glutathione systems play a central role in thiol-disulfide redox homeostasis in many organisms by providing electrons to essential enzymes, and defence …
A Siracusano, P Margutti, F Delunardo… - International journal for …, 2008 - Elsevier
Cystic echinococcosis (CE), a zoonosis caused by the development of Echinococcus granulosus tapeworm larvae in the internal organs of ungulates and humans, continues to …
J Li, WB Zhang, A Loukas, RY Lin, A Ito, LH Zhang… - Gene, 2004 - Elsevier
A full-length cDNA sequence coding for Echinococcus granulosus thioredoxin peroxidase (EgTPx) was isolated from a sheep strain protoscolex cDNA library by immunoscreening …
S Rahlfs, RH Schirmer, K Becker - Cellular and Molecular Life Sciences …, 2002 - Springer
Antioxidant defence plays a crucial role in rapidly growing and multiplying organisms, including parasites and tumor cells. Apart from reactive oxygen species (ROS) produced in …
A Agorio, C Chalar, S Cardozo, G Salinas - Journal of Biological Chemistry, 2003 - ASBMB
Thioredoxin and glutathione systems are the major thiol-dependent redox systems in animal cells. They transfer via the reversible oxidoreduction of thiols the reducing equivalents of …