Current insights on antifungal therapy: Novel nanotechnology approaches for drug delivery systems and new drugs from natural sources

F Sousa, D Ferreira, S Reis, P Costa - Pharmaceuticals, 2020 - mdpi.com
The high incidence of fungal infections has become a worrisome public health issue, having
been aggravated by an increase in host predisposition factors. Despite all the drugs …

Nanoparticles as safe and effective delivery systems of antifungal agents: Achievements and challenges

GM Soliman - International journal of pharmaceutics, 2017 - Elsevier
Invasive fungal infections are becoming a major health concern in several groups of patients
leading to severe morbidity and mortality. Moreover, cutaneous fungal infections are a major …

Nose-to-brain delivery of chrysin transfersomal and composite vesicles in doxorubicin-induced cognitive impairment in rats: Insights on formulation, oxidative stress …

SS Ibrahim, OGA Elseoud, MH Mohamedy, MM Amer… - …, 2021 - Elsevier
Many cancer survivors suffer from chemotherapy-induced cognitive impairment known as
'Chemobrain'. Doxorubicin-topoisomerase II inhibitor-is widely used in breast cancer …

Self-assembly of amphiphilic compounds as a versatile tool for construction of nanoscale drug carriers

R Kashapov, G Gaynanova, D Gabdrakhmanov… - International Journal of …, 2020 - mdpi.com
This review focuses on synthetic and natural amphiphilic systems prepared from straight-
chain and macrocyclic compounds capable of self-assembly with the formation of nanoscale …

Development of acetazolamide loaded bilosomes for improved ocular delivery: Preparation, characterization and in vivo evaluation

AM Mohsen, A Salama, AA Kassem - Journal of Drug Delivery Science and …, 2020 - Elsevier
Acetazolamide (ACZ), a carbonic anhydrase inhibitor, is employed to decrease the
intraocular pressure (IOP) in glaucoma patients. ACZ is characterized by low aqueous …

Formulation of nanospanlastics as a promising approach for‎ improving the topical delivery of a natural leukotriene inhibitor (3-‎ acetyl-11-keto-β-boswellic acid) …

F Badria, E Mazyed - Drug design, development and therapy, 2020 - Taylor & Francis
Purpose The current study aimed to discuss the potential of nanospanlastics as a surfactant-
based vesicular system for improving the topical delivery of 3-acetyl-11-keto-β-boswellic …

Topical nano-vesicular spanlastics of celecoxib: Enhanced anti-inflammatory effect and down-regulation of TNF-α, NF-кB and COX-2 in complete Freund's adjuvant …

E Alaaeldin, HA Abou-Taleb, SA Mohamad… - International Journal …, 2021 - Taylor & Francis
Background Rheumatoid arthritis (RA) is an autoimmune disease that underlies chronic
inflammation of the synovial membrane. Non-steroidal anti-inflammatory drugs (NSAIDs) are …

Formulation and optimization of nanospanlastics for improving the bioavailability of green tea epigallocatechin gallate

EA Mazyed, DA Helal, MM Elkhoudary… - Pharmaceuticals, 2021 - mdpi.com
The present study aimed to investigate the potential of nanospanlastics for boosting the
bioavailability of epigallocatechin gallate (EGCG). EGCG has valuable effects like anti …

The emerging role of extracellular vesicles in fungi: A double-edged sword

Y Lai, B Jiang, F Hou, X Huang, B Ling, H Lu… - Frontiers in …, 2023 - frontiersin.org
Fungi are eukaryotic microorganisms found in nature, which can invade the human body
and cause tissue damage, inflammatory reactions, organ dysfunctions, and diseases. These …

Superficial Dermatophytosis across the World's Populations: Potential Benefits from Nanocarrier-Based Therapies and Rising Challenges

P Keshwania, N Kaur, J Chauhan, G Sharma… - ACS …, 2023 - ACS Publications
The most prevalent infection in the world is dermatophytosis, which is a major issue with
high recurrence and can affect the entire body including the skin, hair, and nails. The major …