Folliculogenesis is a tightly coordinated process essential for generating a fertilization-
competent gamete while also producing gonadal hormones that sustain endocrine function …

Gamete development is a fundamental process that is highly conserved from early
eukaryotes to mammals. As germ cells develop, they must coordinate a dynamic series of …

Ovulation is an integral part of women's menstrual cycle and fertility. Understanding the
mechanisms of ovulation has broad implications for the treatment of anovulatory diseases …

Polycystic ovary syndrome (PCOS) is a highly familial and heritable endocrine disorder.
Over half of the daughters born to women with PCOS may eventually develop their own …

Follicles are the functional unit of the ovary and several methods have been developed to
grow follicles ex vivo, which recapitulate key events of oogenesis and folliculogenesis …

In this chapter, we highlight examples of the diverse array of developmental, cellular, and
biochemical insights that can be gained by using Drosophila melanogaster oogenesis as a …

Across species, ovulation is a process induced by a myriad of signaling cascades that
ultimately leads to the release of encapsulated oocytes from follicles. Follicles first need to …

Ovulation is a critical reproductive process by which a mature oocyte is released from the
ovary for fertilization. This process requires the coordination of multiple cellular and …

Identifying nonhormonal contraceptives will have profound impacts on avoiding side effects
of hormonal birth control methods, minimizing pregnancy complications and infant mortality …

Background/Objectives: The gonadotropins luteinizing hormone (LH) and follicle-stimulating
hormone (FSH) and their receptors are major regulators of reproduction in mammals and …