Monofunctional platinum (II) anticancer agents
S Jin, Y Guo, Z Guo, X Wang - Pharmaceuticals, 2021 - mdpi.com
Platinum-based anticancer drugs represented by cisplatin play important roles in the
treatment of various solid tumors. However, their applications are largely compromised by …
treatment of various solid tumors. However, their applications are largely compromised by …
[HTML][HTML] Metal complexes of saccharin and thiosaccharin as potential anticancer and antimicrobial agents
Based on the chemotherapeutic success of cisplatin, carboplatin and oxaliplatin as
anticancer drugs, and silver sulfadiazine (AgSDZ) as an antibacterial drug, exploration of the …
anticancer drugs, and silver sulfadiazine (AgSDZ) as an antibacterial drug, exploration of the …
New manganese (II), iron (II), cobalt (II), nickel (II) and copper (II) saccharinate complexes of 2, 6-bis (2-benzimidazolyl) pyridine as potential anticancer agents
New mononuclear complexes [Mn (NO 3)(sac)(H 2 O)(bzimpy)]· 2DMF (Mn),[Fe (sac) 2 (H 2
O)(bzimpy)]· 2H 2 O (Fe),[Co (bzimpy) 2](sac) 2· 2H 2 O (Co),[Ni (bzimpy) 2](sac) 2· H 2 O· i …
O)(bzimpy)]· 2H 2 O (Fe),[Co (bzimpy) 2](sac) 2· 2H 2 O (Co),[Ni (bzimpy) 2](sac) 2· H 2 O· i …
The effect of structural configuration on the DNA binding and in vitro antioxidant properties of new copper (ii) N 2 O 2 Schiff base complexes
The interaction of transition metal complexes with DNA and plasma protein gives insight into
the development of new materials for medical and biotechnology applications. Thus, we …
the development of new materials for medical and biotechnology applications. Thus, we …
In vitro anticancer activity of novel Co (II) and Ni (II) complexes of non-steroidal anti-inflammatory drug niflumic acid against human breast adenocarcinoma MCF-7 …
Herein, we report the synthesis, characterization and anticancer activity of six novel
complexes of non-steroidal anti-inflammatory drug niflumic acid with Co (II) and Ni (II). In …
complexes of non-steroidal anti-inflammatory drug niflumic acid with Co (II) and Ni (II). In …
Binuclear silver (I) complexes with the non-steroidal anti-inflammatory drug tolfenamic acid: Synthesis, characterization, cytotoxic activity and evaluation of cellular …
B Harurluoglu, A Altay, S Caglar, EKK Yeniceri… - Polyhedron, 2021 - Elsevier
In this study, two new binuclear silver (I)-tolfenamic acid complexes including picoline
derivative ligands,[Ag 2 (μ-tolf) 2 (2-pic) 2] 1 and [Ag 2 (μ-tolf) 2 (4-pic) 2] 2, were …
derivative ligands,[Ag 2 (μ-tolf) 2 (2-pic) 2] 1 and [Ag 2 (μ-tolf) 2 (4-pic) 2] 2, were …
Recently Reported Biological Activities and Action Targets of Pt (II)-and Cu (II)-Based Complexes
CE Maciel-Flores, JA Lozano-Alvarez… - Molecules, 2024 - mdpi.com
Most diseases that affect human beings across the world are now treated with drugs of
organic origin. However, some of these are associated with side effects, toxicity, and …
organic origin. However, some of these are associated with side effects, toxicity, and …
Zn (II), Cd (II) and Hg (II) saccharinate complexes with 2, 6-bis (2-benzimidazolyl) pyridine as promising anticancer agents in breast and lung cancer cell lines via ROS …
New Zn (II), Cd (II) and Hg (II) complexes of saccharinate (sac) and 2, 6-bis (2-
benzimidazolyl) pyridine (bzimpy),[Zn (bzimpy) 2](sac) 2· 2H2O (Zn),[Cd (sac) 2 …
benzimidazolyl) pyridine (bzimpy),[Zn (bzimpy) 2](sac) 2· 2H2O (Zn),[Cd (sac) 2 …
Nickel complexes of aroylhydrazone ligand: synthesis, crystal structure and DNA binding properties
P Yang, LL Zhang, ZZ Wang, DD Zhang, YM Liu… - Journal of Inorganic …, 2020 - Elsevier
In this work, three aroylhydrazone ligands ((E)-2-hydroxy-N′-(1-(pyrazin-2-yl) ethylidene)
benzohydrazide, HL1;(E)-3-hydroxy-N′-(1-(pyrazin-2-yl) ethylidene) benzohydrazide, HL2; …
benzohydrazide, HL1;(E)-3-hydroxy-N′-(1-(pyrazin-2-yl) ethylidene) benzohydrazide, HL2; …
Synthesis, chemical characterization, PARP inhibition, DNA binding and cellular uptake of novel ruthenium (II)-arene complexes bearing benzamide derivatives in …
M Pavlović, A Tadić, N Gligorijević, J Poljarević… - Journal of Inorganic …, 2020 - Elsevier
Inhibitors of poly (ADP-ribose) polymerase-1 (PARP-1) showed remarkable clinical efficacy
in BRCA-mutated tumors. Based on the rational drug design, derivatives of PARP inhibitor 3 …
in BRCA-mutated tumors. Based on the rational drug design, derivatives of PARP inhibitor 3 …