Recent progress and treatment strategy of pectin polysaccharide based tissue engineering scaffolds in cancer therapy, wound healing and cartilage regeneration

J Koshy, D Sangeetha - International Journal of Biological Macromolecules, 2024 - Elsevier
Natural polymers and its mixtures in the form of films, sponges and hydrogels are playing a
major role in tissue engineering and regenerative medicine. Hydrogels have been …

New trends for osteoarthritis: biomaterials, models and modeling

S Manivong, A Cullier, F Audigié, X Banquy… - Drug Discovery …, 2023 - Elsevier
Highlights•New therapeutic strategies are moving towards nanomedicine and the use of
innovative drug delivery systems to release drugs within the joint.•Ethical considerations …

Construction of Core‐Shell NanoMOFs@ microgel for Aqueous Lubrication and Thermal‐Responsive Drug Release

W Wu, J Liu, P Gong, Z Li, C Ke, Y Qian, H Luo, L Xiao… - Small, 2022 - Wiley Online Library
The construction of porous nanocarriers with good lubricating performance and stimuli‐
responsive drug release is significant for the synergetic therapy of osteoarthritis (OA) …

Pathophysiology to advanced intra-articular drug delivery strategies: unravelling rheumatoid arthritis

H Singh, A Dan, MK Kumawat, V Pawar, DS Chauhan… - Biomaterials, 2023 - Elsevier
Rheumatoid arthritis (RA) is one of the most prevalent life-long autoimmune diseases with
an unknown genesis. It primarily causes chronic inflammation, pain, and synovial joint …

Stimuli‐Sensitive Nanotherapies for the Treatment of Osteoarthritis

Z Wang, S Wang, K Wang, X Wu… - Macromolecular …, 2021 - Wiley Online Library
Osteoarthritis (OA) is a common chronic inflammatory disease in the joints. It is one of the
leading causes of disability with increasing morbidity, which has become one of the serious …

Locally delivered modified citrus pectin-a galectin-3 inhibitor shows expected anti-inflammatory and unexpected regeneration-promoting effects on repair of articular …

Y Zhang, D Su, Y Wang, Z Wang, Y Ren, R Liu, B Du… - Biomaterials, 2022 - Elsevier
Treating the concomitant inflammation in the process of injury and repair, and
simultaneously promoting cartilage regeneration is very important for the repair of articular …

A snowboard-inspired lubricating nanosystem with responsive drug release for osteoarthritis therapy

P Gong, C Li, X Bai, C Qi, J Li, D Wang, J Liu… - Journal of Colloid and …, 2023 - Elsevier
Most of present works of osteoarthritis (OA) therapy are focusing on reducing friction and
improving drug loading capacity, while little attention is paid to realizing long-time lubrication …

Fast nanoparticle rotational and translational diffusion in synovial fluid and hyaluronic acid solutions

M Unni, S Savliwala, BD Partain… - Science …, 2021 - science.org
Nanoparticles are under investigation as diagnostic and therapeutic agents for joint
diseases, such as osteoarthritis. However, there is incomplete understanding of nanoparticle …

[HTML][HTML] Supramolecular microgels/microgel scaffolds for tissue repair and regeneration

K Wang, Z Wang, H Hu, C Gao - Supramolecular Materials, 2022 - Elsevier
Biomedical microgels are a novel type of materials with promising perspectives for repair
and regeneration of multi-types of tissues and organs due to their highly hydrated nature …

A review of recent innovations in cartilage regeneration strategies for the treatment of primary osteoarthritis of the knee: intra-articular injections

NA Householder, A Raghuram… - … Journal of Sports …, 2023 - journals.sagepub.com
Background: The pathology of primary osteoarthritis (OA) begins with structural cartilage
damage, which initiates a self-propagating inflammatory pathway that further exacerbates …