Neurodegeneration is preeminent in many neurological diseases, and still a major burden
we fail to manage in patient's care. Its pathogenesis is complicated, intricate, and far from …

The dual leucine zipper kinase (DLK) alias mitogen-activated protein 3 kinase 12
(MAP3K12) has gained much attention in recent years. DLK belongs to the mixed lineage …

Myelin loss induces neural dysfunction and contributes to the pathophysiology of
neurodegenerative diseases, injury conditions, and aging. Because remyelination is often …

The central nervous system is affected by multiple sclerosis (MS), a chronic autoimmune
illness characterized by axonal destruction, demyelination, and inflammation. This article …

Multiple sclerosis (MS) involves the episodic development of focal inflammatory lesions
causing demyelination and, to a lesser extent, axotomies within the central nervous system …

Infantile hypomyelinating leukodystrophy 19 (HLD19) is a rare genetic disorder where
patients exhibit reduced myelin in central nervous system (CNS) white matter tracts and …

Myelination facilitates the rapid conduction of action potentials along axons. In the central
nervous system (CNS), myelinated axons vary over 100-fold in diameter, with conduction …

Multiple sclerosis (MS) is a chronic inflammatory disease characterized by central nervous
system (CNS) lesions, resulting in axonal loss and physical and cognitive disability. Loss of …

Multiple sclerosis (MS) is an inflammatory and demyelinating disease of the central nervous
system (CNS). The disease is triggered by macrophages and lymphocytes invasion of the …