Photodynamic therapy (PDT) is a minimally-invasive procedure that has been clinically
approved for treating certain types of cancers. This procedure takes advantage of the …

New therapies have been developed using reactive oxygen species produced by light-
activation of photosensitizers (PS). Since the lifetime of these species is extremely short and …

It is recognized that chlorin e6–polyvinylpyrrolidone (Ce6–PVP) formulations are
characterized by a high efficacy in photodynamic therapy of malignant tumors. Currently, a …

Background Chlorin e6 trisodium salt (Ce6) is a newly developed hydrophilic
photosensitizer designed to mediate anticancer photodynamic therapy (PDT). The response …

The uptake and more importantly the subcellular distribution of photosensitizers are major
determinants of their efficacy. In this paper, the cellular internalization of chlorin e6 (Ce6), a …

Nanoparticles engineered to combat cancer and other life-threatening diseases may
significantly improve patient outcomes. However, inefficient nanoparticle delivery to tumors …

Chlorin e6 (Ce6) is among the most used sensitizers in photodynamic (PDT) and
sonodynamic (SDT) therapy; its low solubility in water, however, hampers its clinical …

The photosensitizing properties of three chlorins, meso-tetra (3-hydroxyphenyl) chlorin (m-
THPC), chlorin e6 (Ce6) and meso-tetraphenylchlorin substituted by two adjacent sulfonated …

Oxidation of unsaturated lipids is a fundamental process involved in cell bioenergetics as
well as in cell death. Using giant unilamellar vesicles and a chlorin photosensitizer, we …

Self-assembling peptide-based materials are playing an important role in fabricating drug
delivery carriers; however, they are often limited by several challenges, such as precise …