Titanium and titanium alloys remain the gold standard for dental and orthopedic implants.
These materials are heavily used because of their bioinert nature, robust mechanical …

Abstract Purpose of Review Joint replacement has revolutionized the treatment of end-stage
arthritis. We highlight the key role of macrophages in the innate immune system in helping to …

Objective To investigate the effect of platelet-rich fibrin application on implant stability. Study
design Five databases, namely, PubMed, Embase, Web of Science, Wiley, and China …

While orthopedic implant-associated infections are rare, revision surgeries resulting from
infections incur considerable healthcare costs and represent a substantial research area …

Background Long-lasting reconstruction after extensive resection involving peri-knee
metaphysis is a challenging problem in orthopedic oncology. Various reconstruction …

Bone defects, which can be caused by factors such as trauma, tumor, or osteomyelitis, are
clinically common. They lessen the weight a bone is able to bear and cause severe pain to …

Progressive osteolysis can occur at the cement–bone interface of joint replacements and the
associated loss of fixation can lead to clinical loosening. We previously developed a rat …

The number of total joint replacements (TJRs) in the United States is increasing annually.
Cementless implants are intended to improve upon traditional cemented implants by …

Despite the success of standard antiseptic irrigation solutions in reducing periprosthetic joint
infection (PJI) rates, there is still a need for more effective solutions. Synergistic use of …

An in vivo animal model of a weight‐bearing intra‐articular implant is crucial to the study of
implant osseointegration and aseptic loosening caused by osseointegration failure …