Chemical strategies to engineer hydrogels for cell culture
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …
3D cell culture systems: tumor application, advantages, and disadvantages
O Habanjar, M Diab-Assaf, F Caldefie-Chezet… - International journal of …, 2021 - mdpi.com
The traditional two-dimensional (2D) in vitro cell culture system (on a flat support) has long
been used in cancer research. However, this system cannot be fully translated into clinical …
been used in cancer research. However, this system cannot be fully translated into clinical …
Effects of extracellular matrix viscoelasticity on cellular behaviour
Substantial research over the past two decades has established that extracellular matrix
(ECM) elasticity, or stiffness, affects fundamental cellular processes, including spreading …
(ECM) elasticity, or stiffness, affects fundamental cellular processes, including spreading …
[HTML][HTML] 3D printing of hydrogels: Rational design strategies and emerging biomedical applications
Abstract 3D printing alias additive manufacturing can transform 3D virtual models created by
computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner …
computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner …
Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart
Fibroblasts are a dynamic cell type that achieve selective differentiated states to mediate
acute wound healing and long-term tissue remodeling with scarring. With myocardial …
acute wound healing and long-term tissue remodeling with scarring. With myocardial …
Biomaterials for articular cartilage tissue engineering: Learning from biology
Articular cartilage is commonly described as a tissue that is made of up to 80% water, is
devoid of blood vessels, nerves, and lymphatics, and is populated by only one cell type, the …
devoid of blood vessels, nerves, and lymphatics, and is populated by only one cell type, the …
Three-dimensional cell cultures in drug discovery and development
Y Fang, RM Eglen - Slas discovery: Advancing Life Sciences …, 2017 - journals.sagepub.com
The past decades have witnessed significant efforts toward the development of three-
dimensional (3D) cell cultures as systems that better mimic in vivo physiology. Today, 3D …
dimensional (3D) cell cultures as systems that better mimic in vivo physiology. Today, 3D …
Advances in extrusion 3D bioprinting: a focus on multicomponent hydrogel‐based bioinks
Abstract 3D bioprinting involves the combination of 3D printing technologies with cells,
growth factors and biomaterials, and has been considered as one of the most advanced …
growth factors and biomaterials, and has been considered as one of the most advanced …
Mechanics of 3D cell–hydrogel interactions: experiments, models, and mechanisms
Hydrogels are highly water-swollen molecular networks that are ideal platforms to create
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …
Mechanical confinement regulates cartilage matrix formation by chondrocytes
Cartilage tissue equivalents formed from hydrogels containing chondrocytes could provide a
solution for replacing damaged cartilage. Previous approaches have often utilized elastic …
solution for replacing damaged cartilage. Previous approaches have often utilized elastic …