Cancer cells originate from a series of acquired genetic mutations that can drive their
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …

Microorganisms, including bacteria, viruses, fungi, and other eukaryotes, play critical roles in
human health. An altered microbiome can be associated with complex diseases …

Systematic characterization of the cancer microbiome provides a unique opportunity to
develop cancer diagnostics that exploit non-human, microbial-derived molecules in a major …

Fusobacterium nucleatum is an oral anaerobe recently found to be prevalent in human
colorectal cancer (CRC) where it is associated with poor treatment outcome. In mice …

The commensal microbiota has been implicated in the regulation of a diverse array of
physiological processes, both within the gastrointestinal tract and at distant tissue sites …

Given that only a subset of patients with colorectal cancer (CRC) benefit from immune
checkpoint therapy, efforts are ongoing to identify markers that predict immunotherapeutic …

Fusobacterium nucleatum (Fn) is a dominant bacterial species in colorectal cancer (CRC)
tissue that is associated with cancer progression and poorer patient prognosis. Following a …

Fusobacterium nucleatum has long been found to cause opportunistic infections and has
recently been implicated in colorectal cancer; however, it is a common member of the oral …

Despite decades of research, cancer continues to be a major global health concern. In
recent years, the role played by microorganisms in the development and progression of …

There is mounting evidence that members of the human microbiome are highly associated
with a wide variety of cancer types. Among oral cancers, oral squamous cell carcinoma …