Objective: To estimate the prevalence of NRTI and NNRTI drug resistance mutations in
patients failing NNRTI-based ART in Southern Africa. Study design: We conducted a …

HIV population genotypic tropism testing and its clinical si... : Current Opinion in HIV and AIDS
HIV population genotypic tropism testing and its clinical significance : Current Opinion in HIV …

HIV has caused a global pandemic over the last three decades. There is an unmet need to
develop point-of-care (POC) viral load diagnostics to initiate and monitor antiretroviral …

Background HIV drug resistance (HIVDR) testing was included in the 2017 South African
national HIV household survey. We describe the prevalence of HIVDR by drug class, age …

Background Routine HIV-1 antiretroviral drug resistance testing for patients failing NNRTI-
based regimens is not recommended in resource-limited settings. Therefore, surveys are …

HIV-1 cell entry is mediated by binding to the CD4-receptor and chemokine co-receptors
CCR5 (R5) or CXCR4 (X4). R5-tropic viruses are predominantly detected during early …

Objective To determine the frequency and patterns of acquired antiretroviral drug resistance
in a rural primary health care programme in South Africa. Design Cross-sectional study …

Objectives In low–middle-income countries, increasing levels of HIV drug resistance
(HIVDR) on second-line protease inhibitor (PI)-based regimens are a cause for concern …

Abstract Antiretroviral treatment of Human Immunodeficiency Virus type-1 (HIV-1) infections
with CCR5-antagonists requires the co-receptor usage prediction of viral strains. Currently …

Background: Recurrent tuberculosis (TB) following TB treatment completion in HIV-infected
individuals remains a major public health burden. We assessed the role of various risk …