Late-onset Alzheimer's disease (LOAD) is an age-related neurodegenerative disorder
characterized by gradual loss of synapses and neurons, but its pathogenesis remains to be …

Connexins (Cx) play an important role in the coordination of intercellular communication,
and autocrine and paracrine regulation of cells within the neurovascular unit (NVU). Gap …

Cisplatin plays an essential role in the treatment of various cancers. Cisplatin exhibits high
efficacy, but it often leads to severe neurotoxic side effects, such as chemotherapy-induced …

The hallmarks of Alzheimer's disease (AD) pathology include senile plaques accumulation
and neurofibrillary tangles, which is thought to underlie synaptic failure. Recent evidence …

In subarachnoid hemorrhagic brain injury, the early crucial events are edema formation due
to inflammatory responses and blood‐brain barrier disruption. Baicalin, a flavone glycoside …

Background Oxidative stress formation is pivotal in the action of environmental agents which
trigger the activation of glial cells and neuroinflammation to stimulate compensatory …

Platinum-based chemotherapeutics still play an important role in cancer therapy, however,
severe side effects, such as painful neuropathy, occur frequently. The pathophysiologic …

Blockage along with sudden restoration of blood following ischemia, results in several
cascading events, such as a massive ROS production which plays an important role in the …

Background: There has been a debate on whether sluggish cognitive tempo (SCT) differs
from attention-deficit/hyperactivity disorder (ADHD). Although there have been many studies …

Objective Parkinson's disease (PD) is a debilitating neurodegenerative disorder
characterized by the progressive loss of dopaminergic neurons in the substantia nigra …