Extracellular proteolysis in structural and functional plasticity of mossy fiber synapses in hippocampus

G Wiera, JW Mozrzymas - Frontiers in cellular neuroscience, 2015 - frontiersin.org
Brain is continuously altered in response to experience and environmental changes. One of
the underlying mechanisms is synaptic plasticity, which is manifested by modification of …

[HTML][HTML] Autism as the early closure of a neuroplastic critical period normally seen in adolescence

JM Berger, TT Rohn, JT Oxford - Biological systems, open access, 2013 - ncbi.nlm.nih.gov
The most severe cases of autism are diagnosed by extreme social dysfunction and other
behavioral abnormalities. A number of genetic studies have been conducted to correlate …

Rare variants in tissue inhibitor of metalloproteinase 2 as a risk factor for schizophrenia: evidence from familial and cohort analysis

J John, A Sharma, P Kukshal, T Bhatia… - Schizophrenia …, 2019 - academic.oup.com
Candidate gene and genome-wide association study based common risk variant
identification is being complemented by whole exome sequencing (WES)/whole genome …

The effect of pharmacological inhibition of Serine Proteases on neuronal networks in vitro

S Van De Vijver, S Missault, J Van Soom… - PeerJ, 2019 - peerj.com
Neurons are embedded in an extracellular matrix (ECM), which functions both as a scaffold
and as a regulator of neuronal function. The ECM is in turn dynamically altered through the …

The molecular basis of destabilization of synapses as a factor of structural plasticity

IV Kudryashova - Neurochemical Journal, 2019 - Springer
Within the framework of ideas about structural plasticity as the basis of long-term memory it
has been proven that destabilization of the molecular complex that supports the existing …

Молекулярные основы дестабилизации синапсов как фактор структурной пластичности

ИВ Кудряшова - Нейрохимия, 2019 - elibrary.ru
В рамках представлений о структурной пластичности как основе долговременной
памяти обосновано, что для начала процесса консолидации необходима …

Glutamate treatment and preconditioning differently affect cathepsin B release and intracellular proteases in primary cultures of cerebellar granular cells

AA Yakovlev, AA Kvichansky, AA Lyzhin… - Neurochemical …, 2013 - Springer
Abstract Effects of serum deprivation, preconditioning to serum deprivation, and of glutamate
toxicity on cathepsin B (CB) release and intracellular activities of CB, caspase-3 and calpain …

Роль гиалуроновой кислоты в нейросетевой активности гиппокампа на 26 день in vitro

НМ Ткаченко, АВ Гладков, ИВ Мухина - АКТУАЛЬНЫЕ ПРОБЛЕМЫ …, 2019 - kpfu.ru
Внеклеточный матрикс (ВКМ) представляет собой трёхмерную макромолекулярную
сеть, в которой матричные компоненты связываются друг с другом через рецепторы …

Electrophysiological Effect of uPA Inhibition on Synaptic Plasticity Through Modulation of the Extracellular Matrix

S Van De Vijver, S Missault, J Van Soom… - frontiersin.org
Frontiers | Electrophysiological Effect of uPA Inhibition on Synaptic Plasticity Through
Modulation of the Extracellular Matrix Event Abstract Back to Event Electrophysiological Effect …

[PDF][PDF] Identifying stage-specific markers of Alzheimer's disease using quantitative proteomics

O Yagensky - 2018 - core.ac.uk
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that gradually
impairs memory, cognition and ability to perform simple daily tasks. AD is the most prevalent …