[HTML][HTML] Phytochemicals as modulators of M1-M2 macrophages in inflammation
Macrophages are critical mediators of the innate immune response against foreign
pathogens, including bacteria, physical stress, and injury. Therefore, these cells play a key …
pathogens, including bacteria, physical stress, and injury. Therefore, these cells play a key …
Natural heat shock protein 90 inhibitors in cancer and inflammation
Heat shock protein (HSP) 90 is the most abundant HSPs, which are chaperone molecules
whose major roles are cell protection and maintenance by means of aiding the folding, the …
whose major roles are cell protection and maintenance by means of aiding the folding, the …
Polyphenols as promising drugs against main breast cancer signatures
Breast cancer is one of the most common neoplasms worldwide, and in spite of clinical and
pharmacological advances, it is still a clinical problem, causing morbidity and mortality. On …
pharmacological advances, it is still a clinical problem, causing morbidity and mortality. On …
Antiviral role of phenolic compounds against dengue virus: A review
V Loaiza-Cano, LM Monsalve-Escudero, CSMB Filho… - Biomolecules, 2020 - mdpi.com
Phenolic compounds have been related to multiple biological activities, and the antiviral
effect of these compounds has been demonstrated in several viral models of public health …
effect of these compounds has been demonstrated in several viral models of public health …
Ellagitannin geraniin: a review of the natural sources, biosynthesis, pharmacokinetics and biological effects
HS Cheng, SH Ton, K Abdul Kadir - Phytochemistry reviews, 2017 - Springer
The discovery of the ellagitannin geraniin was made exactly 40 years ago. It is a secondary
metabolite found in plants and is categorised as a hydrolysable tannin under the huge family …
metabolite found in plants and is categorised as a hydrolysable tannin under the huge family …
Natural HSP90 inhibitors as a potential therapeutic intervention in treating cancers: A comprehensive review
Abstract Heat shock protein 90 (Hsp90) has evolved as a cancerous cell growth regulator by
stabilising various oncogenic kinases. Upon the Hsp90 inhibition, the expression of its client …
stabilising various oncogenic kinases. Upon the Hsp90 inhibition, the expression of its client …
Geraniin inhibits LPS-induced THP-1 macrophages switching to M1 phenotype via SOCS1/NF-κB pathway
X Liu, J Li, X Peng, B Lv, P Wang, X Zhao, B Yu - Inflammation, 2016 - Springer
M1 macrophage polarization is proved to promote inflammation in atherosclerosis process.
In this study, we evaluated the inhibitory effect of geraniin, a bioactive polyphenolic …
In this study, we evaluated the inhibitory effect of geraniin, a bioactive polyphenolic …
Targeting cell survival proteins for cancer cell death
Escaping from cell death is one of the adaptations that enable cancer cells to stave off
anticancer therapies. The key players in avoiding apoptosis are collectively known as …
anticancer therapies. The key players in avoiding apoptosis are collectively known as …
Novel benzylidene thiazolidinedione derivatives as partial PPARγ agonists and their antidiabetic effects on type 2 diabetes
Peroxisome proliferator-activated receptor γ (PPARγ) has received significant attention as a
key regulator of glucose and lipid homeostasis. In this study, we synthesized and tested a …
key regulator of glucose and lipid homeostasis. In this study, we synthesized and tested a …
Acalypha wilkesiana flowers: Phenolic profiling, cytotoxic activity of their biosynthesized silver nanoparticles and molecular docking study for its constituents as …
MA El Raey, AM El-Hagrassi, AF Osman… - Biocatalysis and …, 2019 - Elsevier
The bio potential behavior of green silver nanoparticles (AgNPs) using Acalypha wilkesiana
flowers extract weas evaluated. The AgNPs formed were confirmed using surface plasmon …
flowers extract weas evaluated. The AgNPs formed were confirmed using surface plasmon …