A transnosographic approach of negative symptoms pathophysiology in schizophrenia and depressive disorders

SB Guessoum, Y Le Strat, C Dubertret… - Progress in Neuro …, 2020 - Elsevier
Abstract Background: Negative Symptoms (blunted affect, alogia, anhedonia, avolition and
asociality) are observed in schizophrenia but also in depressive disorders. Objective: To …

Use of experimental medicine approaches for the development of novel psychiatric treatments based on orexin receptor modulation

AC Beckenstrom, PM Coloma, GR Dawson… - Neuroscience & …, 2023 - Elsevier
Despite progress in understanding the pathological mechanisms underlying psychiatric
disorders, translation from animal models into clinical use remains a significant bottleneck …

The associations of neutrophil–lymphocyte, platelet–lymphocyte, monocyte–lymphocyte ratios and immune-inflammation index with negative symptoms in patients …

M Šagud, Z Madžarac, G Nedic Erjavec… - Biomolecules, 2023 - mdpi.com
Neutrophil–lymphocyte ratio (NLR), platelet–lymphocyte ratio (PLR), monocyte–lymphocyte
ratio (MLR) and systemic immune-inflammation index (SII index) are increasingly used as …

Physical and social anhedonia are associated with suicidality in major depression, but not in schizophrenia

M Sagud, L Tudor, L Šimunić, D Jezernik… - Suicide and Life …, 2021 - Wiley Online Library
Objective This cross‐sectional study investigated the association of physical and social
anhedonia with suicidality in patients with major depressive disorder (MDD), schizophrenia …

The associations between COMT and MAO-B genetic variants with negative symptoms in patients with schizophrenia

Z Madzarac, L Tudor, M Sagud… - Current issues in …, 2021 - mdpi.com
Negative symptoms of schizophrenia, including anhedonia, represent a heavy burden on
patients and their relatives. These symptoms are associated with cortical hypodopamynergia …

The Use of Ketamine for the Treatment of Anhedonia in Depression

L Patarroyo-Rodriguez, S Cavalcanti, JL Vande Voort… - CNS drugs, 2024 - Springer
Anhedonia, a complex symptom rooted in deficits across reward processes, is primarily
linked to depression and schizophrenia but transcends diagnostic boundaries across …

The effect of vortioxetine on anhedonia in patients with schizophrenia

A Greš, M Šagud, A Dickov - The International Journal of …, 2024 - journals.sagepub.com
Objective Anhedonia is a common symptom of depression, but is also a negative symptom
of schizophrenia. The purpose of this study was to examine the effects of vortioxetine on …

Association between negative symptom domains and happiness in schizophrenia

G Rekhi, M San Ang, J Lee - General Hospital Psychiatry, 2021 - Elsevier
Objective The study aimed to examine the association between levels of self-reported
happiness and different domains and subdomains of negative symptoms (NS), as well as …

[HTML][HTML] The effect of paliperidone palmitate long-acting injectable (PP-LAI) on “non-core” symptoms of schizophrenia: a retrospective, collaborative, multicenter study …

D De Berardis, F Vellante, L Olivieri… - Rivista di …, 2021 - rivistadipsichiatria.it
Background. Schizophrenia is frequently complicated by the occurrence of depressive
symptoms, anhedonia, obsessions and compulsions, suicidal ideation, and substance …

Factores psicosociales relacionados con la recuperación en la esquizofrenia: trauma en la infancia, regulación emocional y apego

RM Hodann Caudevilla - 2022 - docta.ucm.es
Desde mediados del siglo XX, diversos colectivos de pacientes con esquizofrenia se han
opuesto a la visión pesimista del trastorno esbozada por los primeros modelos psiquiátricos …